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199 Cards in this Set

  • Front
  • Back

Most common odontogenic cyst


Most common cyst of oral cavity


at apex of NON VITAL tooth

Periapical (Radicular) Cyst

Types of Odontogenic cysts

inflammatory


developmental


neoplastic

Types of inflammatory odontogenic cysts

periapical


residual periapical


buccal bifurcation

Types of developmental odontogenic cysts

dentigerous/eruption cyst


primordial


lateral periodontal


gingival

types of neoplastic odontogenic cysts

odontogenic keratocyst (keratocytstic odontogenic tumor




calcifying odontogenic tumor

periapical cyst = inflammatory

How do you treat a periapical cyst?

root canal therapy


extraction for non restorable teeth

periapical granuloma

radiographically can't tell diff from cyst




histologically = chronically inflamed granulation tissue of non vital tooth

Inflammatory

Inflammatory

buccal bifurcation cyst

cyst in furcation of most commonly:


Mandibular 1st M


INFLAMMATORY response

Dentigerous cyst


MC DEVELOPMENTAL


encloses crown of unerrupted tooth


MC 3M and C

primordial cyst


enamel organ becomes cyst


most cases are OKC


in place of tooth


Developmental

Lateral


from rest of dental lamina


between 2 roots of vital teeth


Developmental


around transition point mand from ant to post

gingival


developmental


from rests of dental lamina (Serres)


mand C and PM

Calcifying Odontogenic Cyst

GORLIN CYST


NEOPLASM




Odontogenic Keratocyst (OKC)

Odontogenic Keratocyst

Odontogenic Keratocyst

histopath feat= most important


parakeratotic surface epith cells (Wavy)- horizontal


Plaisaded basal cells(fence )- on the bottom borders lighter pink, vertical standing




NEOPLASTIC

Gorlin Syndrome

multiple basil cell carcinomas of the skin


multiple OKC

multiple bcc associated with Gorlin syndrome

basil cell carcinoma ( usually multiple and associated with gorlin syndrome)

intracranial calcification


associated with Gorlin syndrome

What are the 2 odontogenic cysts that may act as a tumor?

OKC can become keratinizing cystic odontogenic turmor (KCOT)




calcifying odont cyst (COC) can become Calcifying cystic odonto tumor (CCOT)

Tumors of odonto epith without odonto ectomesenchyme

ameloblastoma


calcifying epith odonto tumor


squamous odonto tumor



Tumors of odonto epith with ectomesenchyme, with or without dental hard tissue formation

adenomatoid odonto tumor


ameloblastic fibroma


ameloblastic fibro-odontoma


odontoma

Tumors of odonto ectomesenchyme with or without epith



odonto myxoma


cementoblastoma

Ameloblastoma features

multilocular radiolucency




pericoronal radiolucency




extra- osseous (peripheral)

multilocular radiolucency

multilocular radiolucency

can be ameloblastoma (tumor of epith)

pericoronal radiolucency

pericoronal radiolucency

can be ameloblastoma (tumor of epith)

extra osseous
peripheral

extra osseous


peripheral

can be ameloblastoma (tumor of epith)

Histo features of Ameloblastoma

Resembles the enamel organ

Calcifying epithelial odontogenic tumor

Calcifying epithelial odonto tumor




can also look same as ameloblastoma in age location and treatment



Calcifying epithelial odontogenic tumor

histo: cells look like stratum intermedium of enamel organ




has uni and multilocular radiolucency




Tumor of epithelium

Squamous Odontogenic Tumor

from rest of Malassez in PDL space




local radiolucency loss of alveolar bone and lamina dura




tumor of epithelium

squamous odonto tumor




loss of alveolar bone and lamina dura

adenomatoid odontogenic tumor


tumor of epith and ectomesenchyme


involve crown of unerupt tooth


younger pt's ( 10-19)


Females


Maxilla


canine


snowflake calcification

The malignant counter part of ameloblastic fibroma ?

ameloblastic fibrosarcoma

ameloblastic fibroma


tumor of epith and ectomesenchyme


in young pt's

ameloblastic fibro-odontoma




tumor of epith and ectomesenchyme




ameloblastic fibroma of forming tooth tissue

What is the most common type of odontogenic tumor ?

Odontoma : considered developmental anomaly




tumor of epith and ectomesenchyme




pt age avg: 14 yrs




maxilla

compound odontoma (odontogenic tumor)




usually in anterior maxilla




tooth-like structures

complex odontoma




posterior jaws




irregular calcified mass, radiolucent rim

odontogenic myxoma




tumor of ectomesenchyme




soap bubble




local aggressive

cementoblastoma




tumor of ectomesenchyme




benign




radio opaque mass around apex of tooth

What is oral squamous papilloma caused by ?

HPV (6 and 11)

oral squamous papilloma




usually solitary





verruca vulgaris




aka common wart





verruca vulgaris




orally often indistinguishable from oral squamous papilloma




white

condyloma acuminatum




venereal warts - pic in oral cavity




multiples, cauliflower like




caused by HPV 6 and 11



seborrheic keratosis




exclusively skin lesion




stuck on look




associated with sun exposure

actinic lentigo




no intraoral counterpart




from sun exposure




topical retinoic acid reduces color




may be lip lesions

oral melantotic macule




<7mm




usually on lower lip




can occur on soft palate

acquired melanocytic nevus




mole




intraorally- palate and gingiva


may never be pigmented

actinic keratosis




old people




sandpaper feel




from sun exposure




Topical 5-fluorouracil

actinic cheilitis




scaly look




may have ulceration




vermillionectomy




can become cancerous

Tobacco pouch keratosis




grey/ grey-white in area of placement




textured





nicotine stomatitis




grey-white mucosa, multiple papules (red spots in it ) and cracked look

Leukoplakia Definition

a white patch or plaque which can't be characterized clinically or path as any other disease

what is the most common precancerous oral lesion?

leukoplakie= considered premalignant

Leukoplakia




homogenous and speckled




white




worry = tongue, floor of mouth, soft palate




tobacco and alcohol contribute

For which epithelial lesion is a biopsy mandatory?

Leukoplakia

erythroplakia




red




may be adjacent to leukoplakia




most show sever dysplasia




tobacco and alcohol etiology

Oral squamous cell carcinoma

sites: tongue, floor of mouth, soft palate




minimal pain

Oral squamous cell carcinoma

squamous cell carcinoma of lip




from chronic sun exposure




slow growing

Squamous cell carcinoma

spread by lymphs




firm nodes




move or fixed




spreads to lungs, liver, bones




use TMN staging

TNM staging

used with squamous cell carcinoma




stage at diagnosis = most important prognostic indicator




T=tumor size, N= local node involvement, M= distant metastasis

Field cancerization

people with a carcinoma in one place are at increased risk of developing a second mucosal tumor

basil cell carcinoma

low grade malignancy




from chronic sun exposure




in middle 1/3 of face




nodulouclerative = MC form

Melanoma

acute solar damage = really bad sun burn




ABCD's


asymmetry, irreg borders, color variation, diameter >6mm (eraser), evolution

melanoma

oral melanoma

rare




maxillary gingiva, palate

oral melanoma

Osteoma




benign tumor of compact bone




MC site: in posterior mandible

What is the most serious feature of Gardner Syndrome?

Intestinal Polyps


serious because has ability of malignant transformation

intestinal polyps


associated with Gardner syndrome

Gardner syndrome:


intestinal polyps with malignant potential


multiple osteomas


multiple odontomas


supernumerary teeth

Idiopathic Osteosclerosis

increased bone density not attributed to any specific cause


Mandible


PreM and 1st M area


adjacent teeth=vital


NOT condensing osteitis

idiopathic osteosclerosis

Idiopathic osteosclerosis


vs


condensing osteitis

CO= non-vital tooth


widened pdl


sclerosis of bone around root from chronic inflam




IO=increase bone density


adjacent teeth are vital


radioopaque mass

condensing osteitis

traumatic bone cyst

Traumatic bone cyst

asymptomatic


empty cavity


assoc with trauma


pseudocyst

Aneurysmal bone cyst


pseudocyst


Blood soaked sponge=surgical finding


uni/multilocular radiolucency


from rupture of local vascular network in a pre existing bone lesion


Central giant cell granuloma:


non- neoplastic


can be either central or peripheral


Females


Mandible


Anterior


uni/ multi locular radiolucency


assoc with jaw expansion and divergence of tooth roots

peripheral giant cell granuloma

Post- surgical hyperostosis

tumor-like


reactive


growth of bone at surgical site in periosteum after perio surgery ex: gingival graft

3 types of benign Fibro-osseous Lesions of the jaws

Fibrous dysplasia- unknown


central ossifying / cementifying fibroma-neoplasm


cemento-osseous dysplasia - reactive lesion

Fibro-osseous lesions of the jaw

diseases characterized by the replacement of bone with abnormal fibrous CT interspersed with varying amounts of calcification

Fibrous Dysplasia: monostotic =affect only 1 bone- MC type


maxilla


benign and chronic


radiograph- ground glass appearance

polyostotic fibrous dysplasia

Histology of fibrous dysplasia

chinese letters appearance

central ossifying fibroma:


true benign neoplasm


female


mandible


well defined unilocular radiolucency with varying radiopacity

Periapical cemento-osseous dysplasia:


Reactive lesion= not neoplasm


Female


Black


Anterior Mandible


Involved teeth= vital



focal cemento-osseous dysplasia:


Female


White


posterior mandible



florid cemento-osseous dysplasia:


Multiple quads


Black women


Osteomyelitis=complication in edentuolous

Paget's disease:


enlargement and deformity of affected bone


spacing of teeth


headache


dizziness


deafness





paget's disease

cotton wool appearance


associated with paget's disease


hypercementosis in radiographs as well

Histologically, what does paget disease of bone look like?

mosaic pattern


bc prominent reversal lines

What are there significantly high levels of in lab serum in paget's disease?

alkaline phosphatase

Osteoblastoma

benign tumor


cells show osteoblastic differentiation


bone forming


mixed radiolucency





Osteosarcoma


Malignant tumor


bone forming


*sunray or sunburst


* widening PDL

Where is the most frequent intraoral site for metastatic tumors of the jaw?

Mandible


these tumors have begun because of cancers that began in other areas ex:breast, prostate, kidney

Metastatic tumor of jaw


radioopaque

Frictional keratosis


chronic mechanical irritation


calloused mucosa


linea alba= specific type

Endentulous alveolar ridge keratosis



frictional keratosis of tongue

chronic cheek biting


frictional keratosis


irregular thick


can also occur on tongue

Snuff dippers keratosis



amalgam tatoo

graphite tatoo


from pencil


in kids usually

Smoker's melanosis


in facial anterior usually


femal


type of hypermelanosis

Lichen Planus


type of post inflam hypermalanosis (hyperpigmentation)


from inc in melanin synthesis from prostaglandins and other inflam products

Oral melantotic macule


post- inflam hypermelanosis


MC = lower lip

Melanoacanthosis


in African descent pt


after trauma


***need biopsy differ to from melanoma


increased in melanocytes

Where do drug induced pigmentations usually occur?

hard palate and gingiva

Minocycline pigmentation


drug induced

Lead line /poisoning


drug induced pig

Traumatic ulcer


MC cause ulcer in OC = trauma


physical thermal or chemical



Nicotine stomatitis


in heavy smokers


thermal and chemical injury

Cocaine osteonecrosis


cocaine abuse manifest:


palatal perforations


perforated nasal septum


cocaine keratosis


cocaine dehiscence

What drug can cause a chemical burn?

aspirin = necrotic epithelium

Geographic tongue


looks like bald spots elevated borders



Hematoma


submucosal hemorrhage


red dark elevated mass


trauma related


anticoag disorder = predispose

Keloid


abnorm prolif of scar tissue

What is a mucosal alteration that can cause recession of the gingiva ?

lip barbell

What are 2 complications in the oral cavity from chemo?

mucositis


hemorrhage

What are 3 complications that arise in the oral cavity in radiation ?

mucositis


xerostomia


osteoradionecrosis

Chemo related mucositis


moveable tissue = affected most

Chronic hyperplastic pulpitis


growth of granulation tissue from pulp


molars of children

Apical abscess

form of liquefactive necrosis


inflammatory response to bacterial infect or necrosis of pulp



Dental Abscess


accum of neutrophils and exudate and necrotic cells


=PUS

Parulis

Parulis

mass of granulation tissue where sinus tract reaches mucosa

Untreated dental abscess

cellulitis (space infection)


cavernous sinus thrombosis (infection from maxilla)


ludwig angina (infection of mandible )

Periapical granuloma

mass of inflammed granulation tissue at apex of non vital tooth from pulpal necrosis


radiolucent

Internal Resorption


trauma induced


pink crown

What causes pulpal stones ?

Chronic inflammation of the pulp


2 types :


dystrophic calcification


denticles (contain dentinal tubules surrounded by odontoblasts)

Abfraction


wedge shape notch at cervical region


from flex of tooth from pressure

What can cause external resorption?

chronic inflam from trauma


infection


reimplantation of avulsed tooth


orthodontic treatment


tumors ex: ameloblastoma

Osteoradionecrosis


from radiation


moth-eaten appear


mandible

what does the drug bisphosphonate do?

inhibits activity of osteoclasts= slow bone turnover

Clinical indications of bisphosphonate - related osteonecrosis of the jaws?

osteoporosis


cancers that have metastasized to bone


multiple myeloma


paget's disease of bone




ghost outline of sockets 1 yr after extraction

Sialadenitis


MC= mumps = viral form


S. aureus =MC bacterial cause


from result of dec saliva flow or duct obstruct = spread bacteria

Acute sialadenitis of parotid gland

Mucocele


mucous spill into soft tissue from rupture of minor salivary gland duct


trauma


MC= Lower lip

Ranula

mucocele in floor of mouth


from trauma



Superficial Mucocele vs Mucocele

Superficial = minor saliva ducts at surface


from mucosal inflam


clear and bubble like




regular= cause by rupture of duct

Ranula

Salivary duct cyst

mucous retention phenomenon


True cyst


looks like mucocele clinically



Cyst of blandin nuhn


mucocele form in blandin nuhn glands

Salivary stones

partial chronic duct obstruction causes




MC= submandibular gland duct

Sialadenosis


non malig non inflam salivary gland enlarge




from peripheral neuropahty of autonomic nerve supply

Adenomatoid hyperplasia


Inc in # gland acini in minor salivary glands


firm mass


mimick minor salivary gland tumor


MC=hard palate

Necrotizing sialometaplasia


inflammatory


from ischemia-infarction-necrosis and ulcer-slough of necrotic tissue- healing


Posterior palate


heals spontaneously


predisposing: trauma, ill fit denture, adjacent tumor

Sjogren Syndrome

autoimmune disease, affects salivary and lacrimal glands


Primary= xerostomia +dry eye


secondary = primary +chronic inflammatory CT disease (rheumatoid arthritis)




aka dry , irritation

Keratoconjunctivitis


associated with sjogren syndrome

What are 4 signs of Sjogren Syndrome?

keratoconjunctivitis (dry eye)


Swelling of the salivary glands


Raynaud's phenomenon


Oral: atrophy of the dorsal of the tongue




also cervical caries and candidiasis

What is the MC site for salivary gland tumors?

Parotid Gland

Where is the MC site for malignant salivary gland tumors ?

Sublingual gland

Where is the most common anatomical position for minor salivary gland tumors?

Palate

What are the 5 types of benign salivary gland tumors?

Pleomorphic adenoma


Warthin tumor


canalicular adenoma


basal cell adenoma


salivary duct papilloma

Pleomorphic Adenoma


MC salivary neoplasm


benign salivary gland tumor


firm slow grow


Females


Recurrant

Warthin's tumor


MALE


most likely to occur bilaterally


2nd MC benign parotid tumor

Canalicular Adenoma


benign tumor of the salivary gland


exclusive minor salivary gland


MC= upper lip


Female

Mucocele vs canalicular adenoma

Mucocele= from rupture of salivary duct cyst




canalicular adenoma= benign tumor of minor salivary gland

What are the 5 types of malignant salivary gland tumors?

Mucoepidermoid carcinoma


polymorphoud low-grade adenocarcinoma


adenoid cystic carcinoma


acinic cell carcinoma


carcinoma ex- pleomorphic adenoma

What are 3 things that a malignant salivary gland tumor is associated with ?

paresthesia


tumor fixation


ulceration

Mucoepidermoid Carcinoma

MC malignant salivary tumor



Mucoepidermoid carcinoma


parotid= MC site


asymptomatic swelling


can have cyst formation

Polymorphous low grade adenocarcinoma


2nd MC malignant salivary tumor


almost exclusive to minor glands


Palate


**PAIN


bone destruction

Acinic Cell Carcinoma


cells have acinar differentiation


parotid





Carcinoma Ex- pleiomorphic adenoma




malignant salivary gland tumor form of pleiomorphic adenoma formed in an existing one or in a patient that has already had one removed shows sudden rapid growth

What are the 3 P's for bump on gums?

Soft skin lesions=


Pyogenic granuloma


Peripheral Ossifying fibroma


Peripheral Giant cell granuloma

Pyogenic granuloma


Not a true granuloma


non tumor


from trauma


Pregnancy / hormones


bleeds easy


Gingiva

Peripheral Ossifying Fibroma


reactive soft skin lesion


exclusive on gingiva


from PDL


Maxilla


ulcerated



Peripheral giant cell granuloma


blue/purple


exclusive to gingiva/ alveolar ridge


Radiograph= SAUCERIZATION (cupping resorption)

Fibroma


usually along bite line buccal mucosa


smooth pink raised nodule


MC tumor of oral cavity


Prob not true neoplasm


from trauma/ irritation

Traumatic Neuroma


smooth sub mucosal nodule


in mental foramen area


prolif of neural tissue


not true neoplasm


after disrupt schwann cells

What are common drugs that relate to gingival hyperplasia ?

phenytoin


ca channel blockers


cyclosporine

Denture stomatitis


form of candidiasis



Epulis Fissturatum


from ill fit denture


single/multi folds fibrous tissue in vestibule


fibroepithelial polyp = pedunculated lesion of palate from max denture

Inflammatory Papillary Hyperplasia


hard palate


asymptomatic pebbly surface


erythematous


from: ill fit denture, poor OH, wearing denture all the time and superimposed candidiasis



Fibroma


benign tumor of fat


usually in buccal mucosa


normal or yellow color


if cut off floats in water



Schwannoma


benign tumor origin = schwan cell


if oral =tongue usually


can be in bone = unilocular radiolucency

Granular cell tumor


solitary


dorsal of tongue


asymp


tumor of schwann cell origin





Neurofibroma


typical solitary


tongue or buccal mucosa


can occur in bone


multiple=neurofibromatosis assoc- lead to malignant transform

Neurofibromatosis


Multiple neurofibromas


pleixform neurofibroma


cafe au lait pigment


Crowe's sign -armpit freckles


lish nodules - pigment spot on iris of eyes


5% develop neurofibrosarcoma


mental foramen/ alveolar nerve enlarge

What are the 3 types of Lymphangioma?

Capillary-small


Cavernous- med


Cystic (cystic hygroma)- large in neck and armpit

Lymphangioma


usually in posterior triangle


Oral lesions:


TONGUE


frog eggs


deep tumors ill defined masses

Lymphangioma


tongue of pt


frog egg

What is the most common tumor of infancy?

Hemangioma= benign prolif of blood vessiles

Hemangioma


MC tumor infancy


raised red nodular masses of skin


regresses on own

Vascular malformation


***present at birth and persists all life


port wine stains on skin

Hemangioma vs vascular malformation

H= not present at birth, arise in infancy and goes away




VM= present at birth, does not go away

What are the 3 types of soft tissue sarcomas?

Fibrosarcoma


Kaposi's sarcoma


Rhabdomyosarcoma

Fibrosarcoma

Malignant tumor


soft tissue sarcoma


tumor of extremities


grows slow and is painless


Nose and sinus involve most

Karposi's sarcoma


vascular malignant tumor


common in AIDs


4 types:


Classic-old ppl, lower extremities, slow


Endemic-African, benign nodule aggressive


Iatrogenic -organ transplants , aggressive


AID's related-homo males , oral lesion common

Rhabdomyosarcoma


Malignant tumor skeletal muscle


3 types:embryonal, alveolar, pleomorphic(undiff, anaplastic)


MC malignant tumor in kids


Males


orbit, nasal cavity, and nasopharynx


metastatis: embryonal>alveolar>pleomorphic