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20 Cards in this Set
- Front
- Back
Inflammatory response |
1. Blood vessels contract and dilate to move blood to site. 2. Vascular permeability increases so that... 3. White cells and plasma proteins can move through the capillary walls into the tissues to begin the task of destroying the invader in healing the injury site. |
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Mast cells |
Resemble bags of granules, and are the chief activators of the inflammatory response. |
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Mast cells activate the inflammatory response through what 2 functions |
Degranulation and synthesis |
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Degranulation |
The process by which mast cells empty granules from their interior into the extracellular environment. |
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Phase 1 of inflammation |
Acute inflammation if healing is not accomplished move to phase 2 |
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Phase 2 inflammation |
Chronic inflammation if healing not accomplish to move to phase 3 |
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Phase 3 inflammation |
Granuloma formation |
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Phase 4 inflammation |
Healing (may take place after any of the first three phases) |
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Histamine |
Vasoactive amine (organic compound) released during degranulation of mast cells |
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Serotonin |
Released by platelets, can have effects of both vasoconstriction and vasodilation that may affect the blood flow to the affected site. |
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Leukotriene |
Also known as slow reacting substances of anaphylaxis (SRS-A). They have actions similar to those of histamines, vasoconstriction vasodilation and increased permeability as well as chemotaxis |
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Inflammatory response |
Complement system, coagulation system, kinin system |
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Inflammation sequence |
Vascular response, increased permeability, exudation of white cells |
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Monocytes |
Largest normal blood cell. During inflammation they grow several times their original size becoming macrophages. |
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Neutrophils |
The first phagocytes to reach the inflamed site. They ingest bacteria dead cells and cell debris and then they die. |
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Eosinophils |
Primary defense against parasites |
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Hypoxia |
Due to decreased availability of oxygen. Definition: a general oxygen deficiency or oxygen deficiency to a particular tissue or organ. |
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Third-space loss |
Commonly called internal loss because fluid is lost from intravascular or intracellular spaces into interstitial space. |
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Interstitial fluid |
All the fluid found outside the cell membranes, yet not within the circulatory system, making up about 25% of body water |
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Obstructive shock |
Caused by obstruction the interferes with return of blood to the heart, such as pulmonary embolism, cardiac tamponade, or tension pneumothorax. |