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56 Cards in this Set
- Front
- Back
Type IV hypersensitivity Mediated by what? |
T-cell mediated |
|
Type IV hypersensitivity Mediated by what cell? |
T-cell mediated |
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Type IV hypersensitivity Mediated by what?
___- cell __________ |
T mediated |
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Type IV hypersensitivity
Mediated by what? |
T-cell mediated |
|
Type IV hypersensitivity T-cell mediated
How many mechanisms of T cell function that lead to tissue injury? |
2 |
|
Type IV hypersensitivity __- cell mediated
There are _ Mechanisms of _ cell function that lead to tissue ____ |
T 2 T injury |
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Type IV hypersensitivity T-cell mediated
There are 2 __________ of T cell function that lead to ____ injury |
mechanisms tissue |
|
Type IV hypersensitivity
2 mechanisms of T cell function that lead to tissue injury
List |
Delayed hypersensitivity Direct Cell cytotoxicity |
|
Type IV hypersensitivity
_______________ of _ cell function that lead to tissue _________
Delayed hyper________ Direct Cell cyto____________
|
2 mechanisms T injury
hypersensitivity cytotoxicity |
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Type IV hypersensitivity
2 mechanisms of T cell function that lead to tissue injury
Delayed hyper__________ Direct Cell cyto__________ |
sensitivity toxicity |
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Type IV hypersensitivity
2 mechanisms of T cell function that lead to tissue injury
Delayed ____________ Direct Cell ___________ |
hypersensitivity direct cytotoxicity |
|
Type IV hypersensitivity
2 mechanisms of T cell function that lead to tissue injury
___________hypersensitivity ________ Cell cytotxicity |
delayed direct |
|
Type IV hypersensitivity
2 mechanisms of T cell function that lead to tissue injury
____________ hypersensitivity Direct __________ cytotxicity |
Delayed cell |
|
Type IV hypersensitivity
2 mechanisms of T cell function that lead to tissue injury |
Delayed hypersensitivity Direct Cell cytotxicity |
|
Delayed hypersensitivity Direct Cell cytotxicity
These are mechanisms of what? - Cell function - lead to what? |
T cell function tissue injury |
|
Delayed hypersensitivity
Examples
|
TB reaction Persistence of antigen leads to granulomatous inflammation |
|
Delayed hypersensitivity
Examples
_____ reaction __________ of antigen leads to ________ inflammation |
TB persistence granulomatous |
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Delayed hypersensitivity
Example
TB _____ Persistence of ______ leads to granulomatous ________ |
reaction antigen inflammation |
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Delayed hypersensitivity
Example
___________ _____ of ________ _____ to ________________ |
TB reaction persistence antigen leads granulomatous inflammation |
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Delayed hypersensitivity
Example |
TB reaction Persistence of antigen leads to granulomatous inflammation |
|
Type IV hypersensitivity
Name one disease |
Type 1 Diabeties mellitus |
|
Type IV hypersensitivity
Name one disease: Type _ diabetes _____ |
1 mellitus |
|
Type IV hypersensitivity Name one disease: _____ I ______ mellitus |
Type diabetes |
|
Type I diabetes mellitus |
Antigen: pancreatic islet beta cells Results: diabetes |
|
Type I diabetes mellitus
Type of hypersensitivity Antigen Result |
Type IV Pancreatic islet beta cells Diabetes |
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Type I diabetes mellitus
Type of Hypersensitivity Antigen: Pancreatic islet _____ cells Result: diabetes |
IV beta |
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Type I diabetes mellitus
Antigen: _______ islet ____ cells Result: |
Pancreatic beta
diabetes |
|
Type I diabetes mellitus
Antigen: Pancreatic ____ beta _____ Result |
islet cells
diabetes |
|
Type IV hypersensitivity
Notes: Multiple sclerosis |
Antigen: protein antigens of CNS myelin Result: demyelination, paralysis |
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Type IV hypersensitivity
Notes: Crohns disease |
Antigen: unknown, from intestinal microbes Results: chronic inflammation, fibrosis, stricutre |
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Type IV hypersensitivity
Notes: Contact dermatitis |
Antigen: environmental chemicals Result: dermatitis (versicular) |
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Type IV hypersensitivity
Notes: Rheumatoid arthris |
An autoimmune disease Antigen: unidentified antigen in synovium Systemic, chronic inflammatory disease Principle target: joints Can get soft tissue and parenchymal rhematoid nodules |
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Immune diseases
Two category |
Hypersensitivity Immune deficiency disease |
|
Immune deficiency diseases
Categorization |
Can be primary genetic disease or secondary diseases. |
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Immune deficiency diseases
Category
Can be ______ genetic disease or _____ diseases. |
primary secondary |
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Immune deficiency diseases
Category
Can be primary ______ disease or ______ disease |
genetic secondary |
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Immune deficiency diseases
Category
Can be _________ genetic ____ or ________ |
primary disease secondary disease |
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Immune deficiency diseases
Category
Can be _____________ or _____________ |
primary genetic disease secondary disease |
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Immune deficiency diseases
Category |
Can be primary genetic disease or secondary disease |
|
Immune deficiency diseases
Those afflicted are subject to increased susceptibility to __________ |
infections |
|
Immune deficiency diseases
Those afflicted are subject to increased ________ to infection |
susceptibility |
|
Immune deficiency diseases
Those afflicted are subject to ______ susceptibility to _______ |
increased infection |
|
Immune deficiency diseases
Those afflicted are subject to increased susceptibility to infections
Notes |
IgG phagocyte cell deficiences - pyrogenic bacteria
Cell mediated: viruses, fungi, and intracellular bacteria |
|
Primary deficiencies
Cause |
Genetic |
|
Primary deficiencies
Diseases
List |
X-linked agammalglobuniemia (Bruton disease) DiGeorge Syndrome |
|
Primary deficiencies
Diseases
_-linked agammalglobuniemia (Bruton _______) DiGeorge __________
|
X disease syndrome |
|
Primary deficiencies
Diseases
__________ agammalglobunie___ (________ disease) DiGeorge ____________
|
x-linked mia Bruton syndrome |
|
Primary deficiencies
Diseases
___________ agammalglobu__________ (___________) Di__________ Syndrome
|
X-linked niemia Bruton disease George |
|
Primary deficiencies
Diseases
X-linked _______globuniemia (________disease) _____ George Syndrome
|
agammal Bruton Di |
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Primary deficiencies
Diseases
X-linked __________ globu________ (Bruton ______) ____________ Syndrome
|
Agammal niemia disease Digeorge |
|
Primary deficiencies
Diseases
____________ agammal____niemia (__________disease) _____________ Syndrome
|
X-linked globu Bruton
DiGeorge |
|
Primary deficiencies
Diseases
_-linked ___________globu_________ (_______ disease) __________Syndrome
|
X agammal niemia Bruton Digeorge |
|
Primary deficiencies
Diseases
X-linked _______________ (Bruton disease) DiGeorge Syndrome
|
agammalglobulniemia |
|
Primary deficiencies
Diseases
___________________ (________disease) ___________ Syndrome
|
X-linked Agammalglobuniemia (Bruton) DiGeorge |
|
Primary deficiencies
Diseases
________________ (________________) ________________
|
X-linked agammalglobuniemia (Bruton disease) DiGeorge Syndrome
|
|
Primary deficiencies
Diseases
|
X-linked agammalglobuniemia (Bruton disease) DiGeorge Syndrome |