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12 Cards in this Set

  • Front
  • Back
What are the three targets against which chemotherapeutic agents against worms are targetted?
Neural and neuromuscular transmission
Cytoskeletal structure (esp microtubules)
Energy metabolism
What three drugs are used to treat helminthic infections
Bendazoles, Ivermectin, Praziquantel
T/F: Bendazole is the first choice treatment for roundworm infections
False. Filarial infections do not respond to bendazoles. Most other roundworm infections do.
T/F: All filarial infections are treated with ivermectin
False. Almost all filarial infections CAN be treated with ivermectin, but Loa loa cannot.
Praziquantel is used to treat this.
All fluke and adult tape worm infections
Ivermectin is used to treat this.
Almost all filarial infections (not Loa loa)
Bendazoles are used to treat this.
Almost all roundworm infections (not filarial infections)
Metronidazole is used to treat this
Anaerobic protozoa (E. histolytica, Giardia, Trichomonas vaginalis)
Pyrimethamine and sulfadoxine is used to treat this
Toxoplasma gondii and chloroquine-resistant malaria
Bactrim is used to treat this
Pneumocystis and cyclospora
Drugs for treatment of malaria
Chloroquine, mefloquine, pyrimethamine-sulfadoxine, primaquine
These parasites are hard to treat; most of the availabe drugs are toxic.