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5 Cards in this Set

  • Front
  • Back
Abciximab
(ReoPro)
Class: Antithrombotic; Antiplatelet

MOA: Inhibits platelet aggregation by preventing Fibrinogen and other adhesive molecules from binding with receptor sites on active platelets.

Indications: Prevention of cardiac ischemic complications.

Contraindications: Active internal bleeding; Recent GI/GU bleed; Stroke within last 2 years; Thrombocytopenia; Intracranial neoplasm; Vasculitis.

Dosage (adult): 250 mcg/kg, IV bolus followed with maintenance dose of 10 mcg/min for 18-24 hours.

Side Effects: Bleeding; Thrombocytopenia; Rales; Pleural effusion; Bronchospasm; Pulmonary embolism.

Interactions: Anticoagulants, NSAIDs, Dipyridamole, Ticlopidine, and Dextran may increase risk of bleeding.

Onset: Immediate

Duration: 48 hours.

Pregnancy Class: C

Additional Precautions: Monitor for signs of bleeding at all potential sites.
Acetaminophen
(Tylenol)
Class: Analgesic; Antipyretic

MOA: Produces analgesia by elevation of pain threshold and antipyresis through action on hypothalamic heat regulating center.

Indications: Temp. reduction of fever and mild/moderate pain.

Contraindications: Hypersensitivity; Children < 3yo

Dosage (adult): 325-650 mg, PO, every 4-6 hrs.

Dosage (pediatric): 15 mg/kg, PO, every 4-6 hrs.

Side Effects (poisoning): Nausea/Vomiting; Epigastric pain; Diarrhea; Coma; Diaphoresis; Hypoglycemia.

Interactions: None

Onset: 30 min

Duration: 3-4 hrs.

Pregnancy Class: A

Additional Precautions: Consumption of alcohol or malnutrition increase risk for hepatoxicity.
Activated Charcoal
Class: Absorbant

MOA: Binds to toxic substances, inhibiting absorption.

Indications: Acute ingested poison.

Contraindications: Poisoning via Cyanide, Mineral acids, Caustic alkalies, Organic solvents, Heavy metals, Ethanol, and Methanol.

Dosage (all): 1 g/kg, mixed with 6-8 oz water, PO/NG

Side Effects: Nausea/Vomiting; Abdominal cramping; Bloating; Constipation; Diarrhea (from additives).

Interactions: My decrease absorption of other oral medications. Administer at least 2 hrs apart.

Onset: Immediate.

Duration: Unknown

Pregnancy Class: C

Additional Precautions: Most effective when administered ASAP. Within 30 min of ingestion of toxin is preferable.
Adenosine
(Adenocard)
Class: Antidysrhythmic

MOA: Slows conduction time through AV node.

Indications: Conversion of PSVT to sinus rhythm.

Contraindications: Preexisting AV block; Sinus node disease in absence of pacemaker.

Dosage (adult): 6 mg rapid IV. Follow with rapid IV flush. May repeat in 1-2 min at 12 mg.

Dosage (pediatric): 0.1 mg/kg rapid IV. Follow with rapid IV flush. May repeat in 1-2 min at 0.2 mg/kg.

Side Effects: Flushing; Palpitations; A-fib/flutter; Chest pain; Hypotension; SOB; Dyspnea; Numbness; Blurred vision; Nausea/Vomiting; Metallic taste; Transient asystole.

Interactions: Antagonized by Methylxanthines (caffeine, theophylline, etc); Potentiated by Dipyridamole; Carbamazepine may increase degree of produced heart block.

Onset: 20-30 sec

Duration: 10-20 sec

Pregnancy Class: C

Additional Precautions: Monitor ECG, BP, and HR every 15-30 sec for several minutes following administration.
Albuterol
(Proventil; Ventolin)
Class: Sympathomimetic bronchodilator

MOA: Causes relaxation of smooth muscles of bronchial tree, decreasing airway resistance and facilitating mucus drainage.

Indications: Relief of bronchospasm in patients with reversible obstructive airway disease; Acute bronchospasm.

Contraindications: Hypersensitivity

Dosage (adult): 2.5 mg in 3 ml NS, Neb

Dosage (pediatric): 0.15 mcg/kg in 3 ml NS, Neb

Side Effects: Tremor; Anxiety; Nausea; Nasal congestion; Palpitations; Tachycardia; Hypertension; Cough.

Interactions: Other sympathomimetics (such as epinephrine), MAOIs, and Tryciclic antidepresants may potentiate effects; Beta-blocking agents will antagonize effects.

Onset: 5-15 min

Duration: 3-6 hrs

Pregnancy Class: C

Additional Precautions: Children 2-6 yo are more prone to CNS stimulation (hyperactivity, excitement, etc) and GI symptoms.