Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
32 Cards in this Set
- Front
- Back
|
List all the antibiotics
|
Cephalexin Monohydrate
Doxycycline Hyclate Clindamycin HCL Amoxicillin Trihydrate Amoxicillin with Clavulanate Potassium Ciprofloxacin HCL Sulfamethoxazole with Trimethoprim Levofloxacin Azithromycin Dihydrate Mupirocin (topical) |
|
|
List the generic antibiotics
|
All (except for Levofloxacin):
Cephalexin Monohydrate Doxycycline Hyclate Clindamycin HCL Amoxicillin Trihydrate Amoxicillin with Clavulanate Potassium Ciprofloxacin HCL Sulfamethoxazole with Trimethoprim Azithromycin Dihydrate Mupirocin (oint only) |
|
|
Brand name for Cephalexin?
|
Keflex
|
|
|
Dosage forms/strs for Cephalexin?
|
Tabs 250/500mg
Caps 250/500/750mg Powder for oral susp 100mg/ml, 125mg/5ml, 250mg/5ml |
|
|
Indications for Cephalexin?
|
Infection due to:
Strep Staph Klebsiella E. coli P. mirabilis H. influenza |
|
|
MoA for Cephalexin?
|
First gen cephalosporin
Inhibits bacteria cell wall synthesis via acylation of transpeptidase enzyme |
|
|
DIs for Cephalexin?
|
Alters absorption of estrogens including oral contraception
Probenecid incs serum lv of Cephalexin Cephalexin may cause a false positive for: nonspecific urine glucose tests some proteinuria tests Coombs test May falsely elevate urinary 17-ketosteroid values |
|
|
Contras for Cephalexin?
|
Hypersens to penicillins or cephalosporins
Renal function impairment Severe or persistant diarrhea (may cause pseudomembranous colitis) |
|
|
AEs for Cephalexin?
|
N&V
DIARRHEA HIVES ITCHING RASH |
|
|
PxCx for Cephalexin?
|
Take on empty stomach one hour before meal, or two hours after meal with full glass (240ml) of water
Take at even intervals around the clock Complete full course of therapy Keep susp refrigerated, discard unused portion after 14 days Shake susp well before use Report persistent/severe diarrhea |
|
|
Brand name for Doxycycline?
|
Vibramycin
Vibra-Tabs |
|
|
Dosage forms/strs for Doxycycline?
|
Tabs 100mg
Caps 50/100mg Syrup 50mg/5ml Powder for oral susp 25mg/5ml Powder for injection 100/200mg per vial |
|
|
Indications for Doxycycline?
|
Syphilis
Uncomplicated gonorrhea Chlamydia trachomatis Prophylaxis of malaria (Plasmodium falciparum) Infection due to: bacilli cocci spirochetes M. pneumonia rickettsia |
|
|
MoA for Doxycycline?
|
Tetracycline antibiotic
Prevents bacteria protein synthesis by binding to the 30s ribosomal subunit |
|
|
DIs for Doxycycline?
|
Bactericidal antibiotics
Impairs absorption of oral contraceptives Incs BA of digoxin Doxycycline absorption is impaired by Al+, bismuth, Ca+, Mg+, Z+, iron salts, urinary alkalinizers Doxycycline + Methoxyflurane may cause nephrotoxicity |
|
|
Contras for Doxycycline?
|
Hypersens to tetracyclines
Kids under 8 yrs old (tooth development) Impaired renal function |
|
|
AEs for Doxycycline?
|
Dizzy
Vertigo N&V Diarrhea Sensitivity to sunlight Discoloration of forming teeth Sore or darkened tongue Cramps, burning stomach Possible Clostridium difficile associated diarrhea |
|
|
PxCx for Doxycycline?
|
Preferably take on empty stomach one hour before meal, or two hours after meal with full glass (240ml) of water
May take with food or milk if GI upset Take at even intervals around the clock Complete full course of therapy Shake susp well before use Avoid prolonged exposure to sunlight |
|
|
Brand name for Clindamycin?
|
Cleocin
|
|
|
Dosage forms/strs for Clindamycin?
|
Caps 75/150/300mg
Granules for oral soln 75mg/5ml |
|
|
Indications for Clindamycin?
|
Resp tract infections
skin infections septicemia intra-ab infections endometritis and other female infections Use for penicillin allergic pxs |
|
|
MoA for Clindamycin?
|
Prevents bacteria protein synthesis by binding to the 50s ribosomal subunit
It does not cross the BBB |
|
|
DIs for Clindamycin?
|
Potentiates NMBs (neuromuscular blockers)
Clindamycin + Erythromycin decs effectiveness of both |
|
|
Contras for Clindamycin?
|
Severe or persistant diarrhea (may cause pseudomembranous colitis)
|
|
|
AEs for Clindamycin?
|
Ab pain
N&V Diarrhea Puritus Vaginitis Muscle pain Rash |
|
|
PxCx for Clindamycin?
|
Discontinue if rash or severe/persistent diarrhea develops
Complete full course of therapy Drink full glass (240ml) of water after each dose Can take with/without meals |
|
|
Brand name of Azithromycin Dihydrate?
|
Zithromax, Zmax
|
|
|
MoA for Azithromycin?
|
Macrolide antibiotic that binds to the 50s ribosomal subunit, suppressing protein synthesis
|
|
|
DIs for Azithromycin?
|
Food and Antacids slow absorption
Nelfinavir incs serum conc of zmax |
|
|
Contras of Azithromycin?
|
Impaired hepatic
AE: possible pseudomembranous collitis may occur with broad spectrums. |
|
|
AEs of Azithromycin?
|
Diarrhea
N&V Ab pain Injection site irritation |
|
|
PxCx for Azithromycin?
|
Dont take antacids within one hour of Zmax
Shake susp well before use Report severe or persistent diarrhea |
