Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
61 Cards in this Set
- Front
- Back
A benign proliferation of stratified squamos epithelium resulting in a papillary mass appearing as an exophytic granular to cauliflower-like mass is a?
|
Squamous papilloma (Papilloma)
|
|
Presumably, this lesion is induced by HPV subtypes 6 and 11?
|
Squamous Papilloma
|
|
T/F a Squamos Papilloma left untreated will eventually lead to malignancy?
|
False – (there is no malignant potential)
|
|
A benign, virus-induced, focal hyperplasia of stratified squamous epithelium that produces keratin producing a white surface is?
|
Verruca Vulgaris
|
|
Common location of verruca vulgaris when oral mucosa is not involved is? When oral mucosa is involved?
|
Hands, vermillion of lip, labial mucosa or anterior tongue
|
|
A subtype of what virus is found in almost all verrucae?
|
HPV (2, 4, 6, 40)
|
|
A virus-induced proliferation of stratified squamous epithelium of the genitalia, perianal region, mouth and larynx is?
|
Condyloma Acuminatum (Venereal Wart)
|
|
What are the HPV subtypes associated with Condyloma Acuminatum?
|
2, 6, 11, 53
|
|
Multiple, asymptomatic, flat-topped soft nodules which can demonstrate a papillary surface and a cobblestone appearance if clustered would be?
|
Focal Epithelial Hyperplasia
|
|
What subtypes of HPV cause Focal Epithelial Hyperplasia?
|
13, 32
|
|
These localized proliferation of the respiratory mucosa can histomorphologically be divided into three types: fungiform, inverted, and cylindrical cell?
|
Sinonasal Papillomas
|
|
Which of the three types listed above demonstrates the virus?
|
Fungiform
|
|
A Fungiform papilloma will almost exclusively be found where?
|
Nasal Septum (where it causes unilateral nasal obstruction of epistaxis)
|
|
The most common sinonasal papilloma is?
|
Inverted (Schneiderian) Papilloma
|
|
An Inverted Papilloma arises from where?
|
Lateral nasal wall or in a paranasal sinus
|
|
The least common of the sinonasal papillomas is?
|
Cylindrical Cell Papilloma (Oncocytic Schneiderian Papilloma) Found in maxillary antrum, lateral nasal wall and ethmoid sinus
|
|
A viral-induced epithelial hyperplasia of the DNA poxvirus group which shows a small central indentation or keratin-like plug is?
|
Molluscum Contagiosum
|
|
An uncommon lesion found anywhere in the oral cavity which appears as a solitary, pebbly, elevated or depressed lesion would be?
|
Verruciform Xanthoma
|
|
A very common skin lesion of the older adults representing an acquired bengn proliferation of epidermal basal cells which doesn't occur in the mouth is? Has a stuck-on appearance
|
Seborrheic Keratosis
|
|
The sudden appearance of numerous seborrheic keratoses with pruritus and associated with internal malignancy is called?
|
Leser - Trelat sign
|
|
A localized proliferation of sebaceous glands which clinically resembles basal cell carcinomas is?
|
Sebaceous Hyperplasia
|
|
How can you differ Sebaceous Hyperplasia from Basal cell Carcinoma?
|
If you can squeeze stuff out it is not a Basal Cell Carcinoma
|
|
A small hyperpigmented macule of the skin that represents a region of increase melanin production not by an increase of melaoncytes is?
|
Ephelis (Freckle)
|
|
A Benign brown macule caused by chronic UV damage, more common in patients who had freckles as a child is?
|
Actinic Lentigo (Age spot)
|
|
A form of benign cutaneous melanocytic hyperplasia that is small, sharply demarcated and uniformly colored from tan to brown, of unknown cause, and more common on non-sun exposed areas that is thought to be an early stage of a melanocytic nevus is?
|
Lentigo Simplex
|
|
An acquired, symmetric hyperpigmentation of the sun-exposed skin of the face and neck associated with oral contraceptive use is?
|
Melasma
|
|
A flat, pigmented lesion caused by a focal increase in melanin deposition more common on the vermilion of the lower lip is?
|
Oral (Labial) Melanotic Macule (Focal Melanosis)
|
|
A benign acquired pigmentation of the oral mucosa characterized by dendritic melanocytes dispersed throughout the epithelium is?
|
Oral Melanoacanthoma
|
|
Malformations of the skin (mucosa) that are congenital or developmental in nature is giving what term?
|
Nevus (Acquired Melanocytic nevus)
|
|
What clinical stage of Acquired Melanocytic Nevus is the earliest presentation; appears as a brown to black macule, which is sharply demarcated?
|
Junctional nevus
|
|
What are the three clinical stages of Acquired Melanocytic Nevus?
|
Juctional nevus, Compound nevus, Intradermal nevus
|
|
What produces the blue color in a blue Nevus?
|
Tyndall effect
|
|
Leukoplakia, Erythroplakia, and Erythroleukoplakia are all considered what type of oral lesions?
|
Precancerous lesions
|
|
A white patch or plaque that cannot be characterized clinically or pathologically as any other disease thus leading to a diagnosis via exclusion would be?
|
Leukoplakia (know that this term is strictly clinical and does not imply specific histopathologic tissue alteration)
|
|
T/F Leukoplakia is the most common oral precancer?
|
True
|
|
Why is does Leukoplakia show a white color?
|
Thickened surface keratin layer, or thickened spinous layer
|
|
What precancerous lesion has the highest risk malignant transformation?
|
Erythroplakia (erythroplasia)
|
|
Is Leukoplakia more common in males of females
|
Males
|
|
What habit appears to be most associated with leukoplakia development?
|
Tobacco Smoking
|
|
Leukoplakia is usually associated with what pathology?
|
Actinic Cheilosis
|
|
Vermillion of the lower lip that is affected with Leukoplakia most likely is due to?
|
UV radiation
|
|
Which bacteria have been implicated in Leukoplakia?
|
Treponema pallidum (dorsal of tongue in patients with syphilis) and Candida albicans
|
|
T/F currently HPV there is no conclusive evidence that HPV is associated with oral cancer?
|
True
|
|
About 70% of oral leukoplakias are found where?
|
On the lip vermilion, buccal mucosa and gingival
|
|
A special high risk form of leukoplakia characterized by multiple keratotic plaques with rough surface projections althouh initially beginning as a simple flat hyperkeratosis is?
|
Proliferative Verrucous Leukoplakia (almost 100% ---> malignancy)
|
|
What is different about PVL from Leukoplakia?
|
It is more common in Females and has a minimal tobacco association
|
|
Malignant transformation potential of a Leukoplakia is related to what two things?
|
Clinical appearance and degree of dysplasia present
|
|
A red patch that cannot be clinically or pathologically diagnose as any other condition is?
|
Erythroplakia
|
|
Almost all true erythroplakias demonstrate at least one of three things. What are the three things?
|
Epithelial dysplasia, Carcinoma in situ, or invasice squamous cell carcinoma
|
|
An epithelium showing a lack of keratin production that is often atrophic, thus showing a red appearance due to underlying microvasculature is characteristic of?
|
Erythroplakia
|
|
An asymptomatic white fold found in the labial and buccal vestibule of a patient probably means the patient enjoys a little bit of?
|
Smokeless tobacco
|
|
An oral lesion appearing as an area of opacification with a loss of elasticity possibly due to betel nut, or capsaicin would be?
|
Oral Submucous Fibrosis
|
|
What is the greatest significance of oral submucous fibrosis?
|
It is a high-risk precancerous condition
|
|
A common cutaneous premalignant lesion caused by UV radiation to the skin which produces mutations in the p53 suppressor gene is?
|
Actinic Keratosis
|
|
A slowly developing, premalignant lesion of the lower lip that results from chronic or excessive UV light exposure is?
|
Actinic Cheilosis
|
|
A self-limiting epithelial proliferation with a strong clinical and histopathologic similarity to well-differentiated squamous cell carcinoma appearing as a well cicumscribed, firm, elevated lesion with a keratin plug is?
|
Keratoacanthoma
|
|
Approximately 94% of all oral cancers are?
|
Squamous Cell Carcinoma
|
|
What is different in oral cancers in non-smokers vs. smokers? (who is affected etc.)
|
More likely in females, very young patienets, demonstrate mutations involving the p53
|
|
What is the significance of alcohol when pertaining to Oral Cancer?
|
It is a significant potentiator or promoter especially when combined with tobacco
|
|
Oral cancer due to iron deficiency like in Plummer-Vinson Syndrome would most likely be where?
|
Esophagus, Oropharynx and posterior portion of the mouth
|
|
A radiograph appearing as a "moth-eaten" radiolucency with ill-defined or ragged borders could be diagnosed as?
|
Squamos Cell Carcinoma
|