Oral Pathology - Cysts

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Primordial cyst is an uncommon odontogenic cyst, which is defined as

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a cyst that develops in place of a tooth that never developed. It is not a residual cyst. The latter is a cyst left in the jaws following extraction of the associated tooth. The majority of these cysts are odontogenic keratocysts which is why the European literature regards theas synonymous with odontogenic keratocyst.

Front 2

Primordial cyst DDX:

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1. Residual periapical cyst, 2. OKC, 3. Primordial cyst (which is usually OKC), 4. Benign neoplasm i.e. COF (unlikely)

Front 3

Dentigerous Cyst (Follicular Cyst)
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This is a very common odontogenic cyst, accounting for 20% of cysts of the jaw, and is almost always associated with

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the crown of a tooth attached to the cemento-enamel junction. It is believed to originate from the accumulation of fluid between the reduced enamel epithelium and the tooth crown

Front 4

Dentigerous Cyst DDX

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1. DC, 2. OKC, 3. Cystic ameloblastoma

Front 5

The classical dentigerous cyst is not common in deciduous teeth. However, a variant of this cyst, the

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the eruption cyst, is seen commonly with erupting deciduous and permanent teeth. When this cyst is full of blood it is referred to as eruption hematoma. It is believed to originate from accumulation of fluid or blood between the reduced enamel epithelium and the crown of the tooth.

Front 6

DDX: 1. Eruption cyst,

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2. Benign gingival swelling i.e. fibrous hyperplasia, POF, etc.

Front 7

The OKC is well recognized for its tendency for recurrence and its aggressive behavior. This lesion is considered to be more of a "cystic neoplasm" than a true cyst. The most accepted theory of origin is

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from remnants of dental lamina. Overlying surface epithelium is also considered as a significant source of origin.

Front 8

OKC DDX

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DDX: 1. Traumatic bone cavity, 2. OKC, 3. Odontogenic myxoma, 4. Central mucoepidermoid carcinoma.

Front 9

Bifid rib basal cell nevus syndrome (BRBCNS)
This is an autosomal

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dominant with the gene identified as PTCH on chromosome 9q22.3-q31. There is evidence to implicate this gene in the isolated non-syndrome associated OKCs

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BRBCNS DDX

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1. Multiple OKCs, 2. Brown tumor of hyperparathyroidism, 3. Cherubism (unlikely).

Front 11

DDX: 1. Lateral periodontal cyst,

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2. Localized periodontitis (unlikely), 3. OKC (unlikely).

Front 12

DDX: 1. Gingival cyst of the adult,

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2. Lymphangioma, 3. Burn blister.

Front 13

Dental Lamina Cysts of the Newborn (gingival cyst of the newborn) DDX

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DDX: 1. Dental lamina cyst, 2. Gingival abscess (unlikely), 3. Fibroma i.e. giant cell fibroma (unlikely).

Front 14

Epstein's Pearls are...
Bohn's nodules are....

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Epstein's Pearls are cystic nodules along the mid palatine raphae. Bohn's nodules are cystic nodules scattered on the palate especially junction of hard and soft palate.

Front 15

Calcifying Odontogenic Cyst (Gorlin Cyst)
Although this lesion is still classified as a cyst, it is well recognized today that it behaves more like a

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more like a neoplasm than a cyst.

Front 16

DDX: 1. COC

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2. Juvenile ossifying fibroma, 3. Central odontogenic fibroma.

Front 17

DDX: 1. Traumatic bone cavity

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2. OKC, 3. Odontogenic myxoma, 4. Central mucoepidermoid carcinoma, 5. Central hemangioma.;