Oral Pathology #15 - Odontogenic Cyst And Tumors

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develops from seperation of follicle around a crown

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Dentigerous Cyst

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Most common location for dentigerous cyst?

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Mandibular 3rd Molar
Maxillary Canines
Maxillary 3rds

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Dentigerous cyst uniclocular or multilocular?

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Unilocular, can appear multilocular if big enough due to the trabeculation of bone.

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What is the soft tissue analogue of the dentigerous cyst?

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Eruption Cyst

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Eruption cyst are found in what population?

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Children Younger than 10

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Most common site for OKC?

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mandible

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Does OKC expand?

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No, it grows antero-posterior direction within medullary bone

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Describe histology of OKC (3)

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Uniformly thin (6-8 layers)
Devoid of rete pegs
Prominent basal cell layer

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Gorlin Syndrome is also known as?

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Nevoid Basal Cell Carcinoma Syndrome

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Name this syndrome:
Multiple BCCa
OKC
Rib and Vertebral anomalies
Intracranial Calcifications
Palmar & Plantar Pits

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Nevoid Basal Cell Carcinoma Syndrome

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small superficial keratin-filled cysts on alveolar mucosa on infants

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Gingival cyst of the newborn

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Soft tissue counterpart of lateral periodontal cyst

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Gingival cyst

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Most common location for gingival cyst and lateral periodontal cyst?

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75-80% mandibular canine/pre-molar

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Histological hallmark of lateral periodontal cyst and gingival cyst?

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Little out pouchings

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Lateral periodontal cyst with a polycystic appearance

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Botryoid odontogenic cyst

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Cyst where mandible = maxilla in terms of predilection.

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Calcifying Odontogenic Cyst

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Where are calcifying odontogenic cyst most often found?

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65% cases found in incisor canine region

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Most characteristic feature of this cyst are ghost cells

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Calcifying Odontogenic Cyst

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Most common clinically significant odontogenic tumor?

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Ameloblastoma

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Ameloblastoma arise from?

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Cell rests of dental lamina
Developing enamel organ
lining of odontogenic cysts
basal cells of oral mucosa

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Ameloblastoma with multiple islands of odontogenic epithelium

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Follicular Pattern

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Ameloblastoma with histology of anastomosing cords of odontogenic epithelium

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Plexiform pattern

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epithelial tumor with inductive effect on odontogenic ectomesenchyme

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Adenomatoid Odontogenic Tumor

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Odontogenic Tumor where females 2x males

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Adenomatoid Odontogenic Tumor

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Snow flake calcifications

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Adenomatoid Odontogenic Tumor

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Adenomatoid Odontogenic Tumor most commonly found in what location?

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75% circumscribed unilocular RL that involves crown of unerupted tooth, most often canine

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Histology of tumor shows rosettelike structures about central space

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Adenomatoid Odontogenic Tumor

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Also known as Pindborg Tumor

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Calcifying epithelial Odontogenic Tumor

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Liesegang ring calcifications are found in what tumor?

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Calcifying Epithelial Odontogenic Tumor

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Where are calcifying epithelial odontogenic tumor most often found?

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Posterior Mandible

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True mixed tumor of epithelial and mesenchymal elements

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Ameloblastic Fibroma

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Most common site for ameloblastic fibroma

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posterior mandible

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Gorlin cyst is aka?

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calcifying odontogenic cyst

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soap bubble or honey combed on radiograph is indicative of?

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Ameloblastoma

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Three types of ameloblastoma in order of most common to least.

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Convetional solid or multicystic (86%)
unicystic (13%)
peripheral (1%)