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30 Cards in this Set

  • Front
  • Back

review: types of pain


causes of cancer pain in advanced cancer


Pain that isn't constant: 3 types

1. intermittent pain: comes and goes, always same location and type of pain, may be managed with prn analgesia


2. breakthrough: episodes of pain superimposed on baseline pain may occur spontaneously or following some activity


3. incident pain: subtype of breakthrough pain that occurs during activity and ceases with rest

Edmonton Classification System For Cancer Pain (PANIC mnemonic)



it can take time to optimize pain control in cancer...

d

WHO analgesia ladder for cancer pain



acetaminophen dosing


1. short term use, healthy p.


2. chronic use, healthy p


3. chronic use, unhealthy/at risk p.




risk factors for hepatotox 5



risks of NSAIDS? (>2 mo use)







opioid myths...



considerations in opioid prescribing



List


1 weak opiod


5 strong opioids



which drug SHOULD NOT BE PRESCRIBED for cancer pain



should know these...


6 early adverse effects of opioids



7 late adverse effects of opioids



Opioid induced neurotoxicity? 5




considering this has "Exam question" written below..

consider DDx.. infection, titration too rapid, dehydration

consider DDx.. infection, titration too rapid, dehydration

EXAM: how to pick up and treat opioid toxicity (4 tx points)



types of opioids available, short acting (6) and long-acting (5) formulations



suggested starting doses for Morphine




NB: EXAM QUESTION: STARTING DOSE MORPHINE



special considerations for...




opioid naive patient

no codeine

special considerations for...




renal failure/impairment

often change to less frequent dosing, down to even qd

special considerations for...




liver failure/impairmemnt

Glucuronidation is generally more resistant toproblems in liver impairment (morphine and hydromorphone clearance is dependent on glucuronidation)




Opioids not generally contraindicated in mild to moderate liver failure




drop the dose and/or increase interval by 1.5-2 times

NB: How to write orders for opioid


5 aspects to hit



how to adjust opioids with interventional pain treatment



important: opioid risk tool for assessing risk of abuse



a few different things to consider: physical dependence, addiction vs. pseudo-addiction, tolerance

d

pitfalls in cancer pain..



example of non-pharmacologic adjuvants 7



pharmacologic adjuvants for


bone pain (2)


neuropathic pain (4)


other



pharmacological management of non-cancer neuropathic pain?





other important considerations for prescribing opioids.. 4