Omb Cardiac Pharmacology

Front 1

Nitrates

MOA

Back 1

Increase NO
Increase cGMP >>
Vasodilation (venous > arteriolar)

Front 2

Nitrates

USES

Back 2

Angina
(decrease preload & afterload)

Cyanide poisoning

Front 3

Nitrates

SE

Back 3

H/A
Tolerance: "Monday Disease"

CONTRA: Sildenafil

Front 4

IV Nitrate

NAME & USE

Back 4

Nitroprusside

HTN Crisis
Aortic Dissection

Front 5

Non-dyhydropyridine CCB's

NAMES & MOA

Back 5

Verapamil & Diltiazm

Block L-type Ca channel

Front 6

Non-dyhydropyridine CCB's

USES

Back 6

PVST
AFIB/Flutter

Front 7

Non-dyhydropyridine CCB's

SE

Back 7

Precipitate AV Block

Constipation

Front 8

Dyhydropyridine CCB

MOA

Back 8

-dipine

Block slow CA channels

Front 9

Dyhydropyridine CCB

USES

Back 9

HTA

Front 10

Dyhydropyridine CCB

SE

Back 10

Constipation
Reflex tachycardia

Front 11

Ranolazine

MOA

Back 11

Partial FA oxidation (-)

Front 12

Ranolazine

USES

Back 12

Refractory angina

Hint 12

Ran over CAT I

Front 13

Ranolazine

SE

Back 13

Long QT

Front 14

Digoxin

MOA

Back 14

(-) Na/K ATPase
Increase Ca (Inotropic)

Front 15

Digoxin

USES

Back 15

CHF
AFIB

Front 16

Digoxin

SE

Back 16

Distorted color/blurry vision
Hypokaelmia Increases Toxicity

TX OD: DigiFAB

Front 17

Dobutamine

MOA

Back 17

B1 (alpha 1) Agonist

Front 18

Dobutamine

USES

Back 18

CHF

Front 19

Class IA Anti-Arrhythmics

NAMES & MOA

Back 19

Disopyramide
Quinidine
Procainamide

Na (& K) Channel Blockers

Hint 19

Double
Quarter
Pounder

Front 20

Class IB Anit-Arrhythmics

NAMES & MOA

Back 20

Lidocaine
Tocainide
Mexiletine

Na Channel Blockers

Hint 20

Lettuce
Tomato
Mexican

Front 21

Class IC Anti-Arrthymics

NAMES & MOA

Back 21

Moricizine
Flecainide
Propefenone

Na Channel Blockers

Hint 21

More
Fries
Please

Front 22

Class II

NAMES & MOA

Back 22

Non Selective Beta Blockers
Propranalol

Selective Beta Blockers
Metoprolol, Esmolol

Front 23

Class III

NAMES & MOA

Back 23

K Channel Blockers

Amiodarone
Dofetillide, Ibutilide
Sotalol

Front 24

Class IV

Names and MOA

Back 24

Non-Dihydropyridine CCB's
Verapamil, Diltiazem

Block L-type Ca channels

Front 25

Quinidine

SE

Back 25

Cinchonism
Tx: NaHCO3

CONTRA: Asthma, COPD, DM

Front 26

Propanolol

USES

Back 26

Tx: Thyroid Storm

Tremor

Front 27

Beta Blocker

OD TX

Back 27

Glucagon

Front 28

Amiodarone

SE

Back 28

Pulmonary Fibrosis

Inhibits CYP-450

Increased Incidence of Torsades de Pointes

Front 29

Class III
Sotalol, Dofetillide, Ibutilide

SE

Back 29

Increased Incidence of Torsades de Pointes

Front 30

Statins

MOA

Back 30

(-) HMG-CoA reductase

Increase LDL receptors in liver
Decreases LDL Plasma Cholesterol

Front 31

Statins

USES

Back 31

1st Line Tx: Increased LDL

Front 32

Statins

SE

Back 32

Rhabdomyolysis

Check LFT's & CK's

CONTRA: Pregnancy, breast feeding

Front 33

Niacin

MOA

Back 33

Increases HDL
Increases Lipoprotein Lipase

Front 34

Niacin

USES

Back 34

Hyperlipidemias

Front 35

Niacin

SE

Back 35

Histamine flush
Gout

Front 36

Fibrates

MOA

Back 36

PPAR alpha (-)

Increases Lipoprotein Lipase

Front 37

Fibrates

USES

Back 37

Increased TG
Increased Lipoproteinemia

Front 38

Fibrates

SE

Back 38

Gallstones

Front 39

Bile Acid Sequestrants
(-Chol-)

MOA

Back 39

Increase Bile Acid excretion in feces

(Increase chol conversion to bile)

Front 40

Bile Acid Sequestrants
(-Chol-)

USES

Back 40

Reduce itching from cholestasis

Front 41

Ezetimibe

MOA

Back 41

Sterol uptake (-)
Blocks intestinal absorption of cholesterol & phytosterols

Front 42

Ezetimibe

USES

Back 42

Hypercholesterolemia

Front 43

Nitroprusside

USES

Back 43

HPTN Crisis

Aortic Dissection

Front 44

Bosentan

MOA

Back 44

Antagonist at Endothelin 1 Receptor (ETA)

vasoconstriction

Endothelin B (ETB)
(NO Release)