Ocular Disease: Skin Terms

Front 1

Acantholysis

Back 1

seperation of epi cells

Front 2

Acanthosis

Back 2

THICKENING of sq cell layer, because increase in keratocytes

seen in seborrheic keratosis

Front 3

Actinic keratosis

Back 3

epi dysplasia

(often seen with inflam and elastosis)

Front 4

Adnexal

Back 4

pertaining to sweat glands

Front 5

Adenoma

Back 5

Benign tumor of gland

Front 6

Anaplasia

Back 6

loss of differentiation of cells, often increases ability to multiply > an in malignant tumor

Front 7

Atypia

Back 7

normal nuc:cytoplasm ratio is altered in favor of the nuc (hyperchromasia)

Front 8

Carcimona in situ

Back 8

full thickness dysplasia

Front 9

Bulla

Back 9

Blister >5mm

Front 10

Carcinoma

Back 10

malignant neoplasm derived from cells of epi origin (entoderm or ectoderm)

Front 11

Caseation

Back 11

tissue necrosis

resulting in loss of structure and replacement by amorphous cheesy material

"camembert cheese caseates"

Front 12

Choristoma

Back 12

tissue in the wrong place

(a neoplastic tumor compromised of well differentiated histologically normal cells and tissue that occur normally in come body site, but are not normally found in the affected tissue)

Front 13

Crust

Back 13

concretion on the surface of a wound

Front 14

Dysplasia

Back 14

abnorm maturation of epidermis

Cells loose polarity and may become atypical.

Polarity refers to the norm arrangement of cells within a tissue. Atypia occurs when the normal nuc:cytoplasm ratio is altered in favor of the nuc. Dysplasia may be full or partial thickness. Full dysplasia > carcinoma in situ

Front 15

Dyskeratosis

Back 15

Keratinization in epidermis cells

Assoc with: SCC.

Has a malignant flavor to it.

Front 16

Ecchymosis

Back 16

Blood in tissue spaces

Front 17

Elastosis

Back 17

caused by UV damage to skin

Assoc with:AK, SCC, BCC, Melanoma

Front 18

Erythema

Back 18

redness (from vasc dilaiton)

Front 19

Excoriation

Back 19

Denuded skin secondary to scratching

Front 20

Exfoliate

Back 20

shed in broad scales

Front 21

Filiform

Back 21

thread like

Front 22

Follicular Plug

Back 22

compact keratin within follicular orifice

Front 23

Granuloma

Back 23

nodular PROLIFERATION of INFLAM CELLS

consists of lympocytes, histio-cytes, macrophages, giant cells

Front 24

Hamartoma

Back 24

increase in number of cells

Front 25

Hyperkeratosis

Back 25

fingernail consistency

Front 26

Keratinization

Back 26

epi cells making keratin, which builds corns and horns

Front 27

Keratoma

Back 27

papule/nodule having a scaly/horny layer

Front 28

Keratosis

Back 28

localized keratinized overgrowth of the upper epi layers (squamous) of skin.

Ie: AK and Seborrheic Keratosis

Front 29

Lichenification

Back 29

thickened skin with accumulated markings due to epidermal hypertrophy

Front 30

Macule

Back 30

flat lesion with diff color than normal skin

Front 31

Melanophage

Back 31

histiocyte which has ingested melanin particles

Front 32

microabscess

Back 32

small foci of neutrophils

Front 33

Neoplasm

Back 33

growth that does not respond to norm growth restraining mech of body

Benign: slow, grows expansively
Malignant: rapid, ability to infiltrate, removal often not enough

Front 34

Nodule

Back 34

elevated lesion >1cm

Front 35

Papilloma

Back 35

lesion with nipple-like configuration

Front 36

Papillomatosis

Back 36

nipple-like extensions of the dermal papilla upward into an irreg epidermis

Front 37

Papule

Back 37

elevated lesion ,1cm

Front 38

Parakeratosis

Back 38

occurs when nuc are retained in the superficial keratin layer. The granular layer my be thin or absent.

Parakeratosis is seen in conditions of rapid epithelial cell turnover, such as psoriasis and SCC.

Front 39

Petechia

Back 39

minute hem into skin

Front 40

Pilosebaceous

Back 40

pertaining to hairfollicle-sebaceous unit

Front 41

Plaque

Back 41

a solid plateau-like elevated lesion

Front 42

Polarity

Back 42

tissue polarity refers to the arrangement of cells within a tissue.

Normal polarity of skin: basal layer, prickle, squamous layer

Front 43

Purpura

Back 43

hem in skin (medium size)

Front 44

Diff size hem in skin

Back 44

Petachiae < Pupura < Ecchymosis

Front 45

Pustule

Back 45

bunch of inflam cells

Front 46

Sarcoma

Back 46

Malignant neoplasm derive from mesenchymal origin. Includes muscle, bone, blood vessels and blood forming tissue.

Front 47

Spongiosis

Back 47

intercellular edema resulting in the widening of the space between keratinocytes

Front 48

Telangiectasia

Back 48

small superficial dilated vessel

Front 49

Tumor

Back 49

localized swelling or mass.

Front 50

Vesicle

Back 50

blister cavity < 5mm

Front 51

Verrucous

Back 51

wartlike