Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
27 Cards in this Set
- Front
- Back
Which of the following is a common cause of hirsutism and virilization?
|
Polycystic ovarian disorder
|
|
Hirsutism and virilization are characterized as
|
androgen-excess disorders
|
|
Which of the following is a major function of androgens in women?
|
Precursor for estrogen biosynthesis
|
|
The treatment for androgen-excess disorders is directed at
|
suppression of source of androgen
|
|
What histologic structure is characteristic of teh hilus cell tumor?
|
Reinke crystalloid
|
|
Hirsutism is most frequently associated with
|
development of acne
|
|
Which is the first event usually associated with virilization?
|
Enlargement of the clitoris
|
|
In adipose tissue, there is extraglandular production of testosterone from
|
androstenedione
|
|
In hair follicles, dihydrotestosterone is produced by the local action of 5-alpha-reductase on
|
testosterone
|
|
What percent of testosterone is not bound to sex hormone-binding globulin (SHBG)?
|
1 to 3%
|
|
The hepatic production of sex hormon-binding globulin is stimulated by
|
estrogen
|
|
In women, the most common cause of hirsutism associated with androgen excess is
|
polycystic ovarian disease
|
|
Which of the following is inconsistent with the diagnosis of polycystic ovarian disease?
|
Virilization
|
|
Which of the following is a characteristic finding in women with polycystic ovarian disease?
|
Androstenedione at the upper limits of normal or increased
|
|
Successful treatment of polycystic ovarian syndrome with oral contraceptives should result in
|
decreased ovarian androgen secretion
|
|
An example of virilization caused by polycystic ovarian syndrome is
|
acanthosis nigricans
|
|
Sertoli-Leydig cell tumors are characterized by increased
|
testosterone secretion
|
|
Patients with Sertoli-Leydig cell tumors typically have
|
an elevated level of testosterone
|
|
The surgical removal of a unilateral Sertoli-Leydig cell tumor should result in the reveral of which symptom?
|
Amenorrhea
|
|
Which of the following is characteristic of gynandroblastoma?
|
Granulosa cell and arrhenoblastoma components
|
|
Which of the following is characteristic of lipid (lipoid) cell tumors?
|
Small tumor containing sheets of round, clear, pale staining cells
|
|
Which of the following is most likely to be positively affected following medical treatment of adrenal hyperplasia with prednisone?
|
Ovulation
|
|
Which of the following is characteristic of 11 beta-hydroxylas deficiency?
|
Increased serum desoxycorticosterone
|
|
Women with constitutional hirsutism are characterized by
|
greater activity of 5-alpha-reductase
|
|
The potent metabolite of testosterone that is produced in genital skin and hair follicles is
|
dihydrotestosterone DHT
|
|
Which of the following is associated with hirsutism?
|
Excess body hair
|
|
An elevated 24-hour-free cortisol level is suggestive of what condition?
|
Cushing disease
|