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12 Cards in this Set
- Front
- Back
Gliosis |
Proliferation and hypertrophy of glial cells. |
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Neuron AP depends on? |
Leakage of K out of cell. |
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Local anaesthetics effects on neurons? |
Block Na chs inhibiting signaling. Ex. Lidocaine, benzocaine, tetracaine. Cocaine, tetradotoxin |
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Caps of astrocytes |
Remove excess NTs.
GFAP marker for ID astrocytomas. Commonly infected by JV virus in HIV pts causing PML. |
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Caps of microglia |
Proliferate in response to injury. HIV infection causes chronic HIV encephalitis. |
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Caps of oligodendroglia |
Destropyed in MS. |
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Caps of Schwann cells |
Destroyed in Guillain-Barre Syndrome. Formation of schwanomas affecting CN VIII, "acoustic neuromas". |
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How do nerves sense? |
- Free nerve endings - Meissner's corpuscles - Pacinian corpuscles - Merkel's discs |
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Free nerve endings |
Found in skin. For sensation of pain & temperature. Use C & A-delta fibers. |
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Meissner's corpuscles |
Found in surface of skin, mostly in hairless areas. For sensation of touch. Uses A-alpha fibers. Rapid adapting! |
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Pacinian corpuscles |
Found in deep skin, joints & ligaments. For sensation of vibration & pressure. Egg shaped! Uses A-alpha fibers. Rapid adapting! |
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Merkel's discs |
Found mainly in hair follicles. For sensation of pressure & position. Uses A-alpha fibers. Slow adapting! |