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12 Cards in this Set

  • Front
  • Back

Gliosis

Proliferation and hypertrophy of glial cells.

Neuron AP depends on?

Leakage of K out of cell.

Local anaesthetics effects on neurons?

Block Na chs inhibiting signaling.



Ex. Lidocaine, benzocaine, tetracaine. Cocaine, tetradotoxin

Caps of astrocytes

Remove excess NTs.



GFAP marker for ID astrocytomas.


Commonly infected by JV virus in HIV pts causing PML.

Caps of microglia

Proliferate in response to injury.




HIV infection causes chronic HIV encephalitis.

Caps of oligodendroglia

Destropyed in MS.

Caps of Schwann cells

Destroyed in Guillain-Barre Syndrome.




Formation of schwanomas affecting CN VIII, "acoustic neuromas".

How do nerves sense?

- Free nerve endings


- Meissner's corpuscles


- Pacinian corpuscles


- Merkel's discs

Free nerve endings

Found in skin.




For sensation of pain & temperature. Use C & A-delta fibers.

Meissner's corpuscles

Found in surface of skin, mostly in hairless areas.




For sensation of touch. Uses A-alpha fibers.




Rapid adapting!

Pacinian corpuscles

Found in deep skin, joints & ligaments.




For sensation of vibration & pressure. Egg shaped! Uses A-alpha fibers.




Rapid adapting!

Merkel's discs

Found mainly in hair follicles.






For sensation of pressure & position. Uses A-alpha fibers.




Slow adapting!