Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
42 Cards in this Set
- Front
- Back
|
T or F: Primary brian tumors are the most common solid tumors in the first decade of life
|
TRUE
|
|
|
T or F: Brain tumors don't generally cause mass effect
|
FALSE
|
|
|
What makes intrinsic brain tumors lethal
|
invasion
|
|
|
Where are most primary brain tumors?
|
frontal lobes (and temporal)
|
|
|
What are the 5 classes of brain tumors?
|
Glial tumors
Meningeal tumors Peripheral nerve tumors Embryonal tumors Mets |
|
|
What are some examples of glial tumors?
|
astrocytomas, oligodendrogliomas, ependymomas
|
|
|
What are some examples of meningeal tumors
|
meningiomas
|
|
|
What are some examples of peripheral nerve tumors?
|
Schwannomas and neurofibromas
|
|
|
What is an example of an embryonal tumor
|
medulloblastoma
|
|
|
Gliomas account for __% of all tumors and __% of malignant tumors of the brain
|
40% of all tumors and 78% of malignant tumors
|
|
|
What are the most common brain tumors of the brain?
|
meningiomas
|
|
|
What is the most common brain tumor in pts over 20 yo?
|
glioblastomas
|
|
|
What are the most common brain tumors in the first 2 decades of life?
|
medulloblastoma
|
|
|
Which tumor has the worst prognosis?
|
glioblastomas
|
|
|
Solid glioma that is well circumscribed, solid and cystic found in the cerebellum, hypothalamus, or optic nerve --> __
|
pilocytic astrocytoma (WHO grade I)
|
|
|
kids or adults more: pilocytic astrocytoma
|
kids
|
|
|
What are Rosenthal fibers and Eosinophilic granular bodies?
|
brightly eosinophilic fibers seen in pilocytic astrocytoma that are remnants of degenerating axons, etc. indicative of a slow-growing process.
|
|
|
Diffuse infiltration by cytologically atypical cells that are diffuse and hyperdense on T2 non-con MRI. What kind of glioma?
|
Diffuse astrocytoma (WHO grade II)
|
|
|
What is a grade III astrocytoma?
|
Anaplastic astrocytoma
|
|
|
Which astrocytoma has variable MRI appearance, and histo similar to diffuse astrocytoma with increased mitotic activity?
|
Anaplastic astrocytoma
|
|
|
Which is a grade II glimoa?
|
Diffuse astrocytoma (WHO grade II)
|
|
|
What is a grade IV astrocytoma?
|
glioblastoma
|
|
|
What astrocytoma presents as a single ring enhancing lesion on T1 MRI?
|
glioblastoma
|
|
|
Which astrocytoma has microvascular proliferation and necrosis(pseudopalisading)?
|
glioblastoma
|
|
|
Which gliomas are frequently calcified?
|
oligodendrogliomas
|
|
|
What is the signature molecular event of oligodendrogliomas?
|
deletion of 1p and 19q (usually an unbalanced translocation)
|
|
|
Which non-diffuse glioma typically grows in the cerebellum and spinal cord?
|
ependymomas
|
|
|
Which glioma can seed the CSF?
|
ependymomas
|
|
|
perivasuclar rosette -->
|
ependymomas
|
|
|
What is a useful diagnostic feature of meningioma on T1 MR w/ con?
|
dural tail
|
|
|
Which tumor takes up contrast the best?
|
meningiomas
|
|
|
What grade are typical meningiomas?
|
WHO grade I
|
|
|
What are some familial cancer syndromes?
|
NF1, NF2, TSC, vHL, etc.
|
|
|
Which PNS tumor expands the nerve sheath?
|
Neurofibromas
|
|
|
Bilateral acoustic schwannoma -->
|
NF2
|
|
|
Which tumor has biphasic (hypo and hyper cellular areas)?
|
Schwannomas
|
|
|
what are verocay bodies and where are they seen?
|
nuclear palisades surrounding acellular zones seen in Schwanomas
|
|
|
Which tumor occurs in the posterior fossa or cerebellum only?
|
medulloblastoma
|
|
|
What is the grade of medulloblastoma?
|
WHO grade IV
|
|
|
T or F: Medulloblastomas typically seed the CSF
|
TRUE
|
|
|
What is the most common "brain" tumor
|
mets from somewhere else
|
|
|
What are the most common sources of mets to the brain?
|
lung, breast, skin (melanoma), kidney (rcc)
|
