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9 Cards in this Set

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What kind of neoplasm and its abnormalities?

What kind of neoplasm and its abnormalities?



Liomyoma


Benign- well circumscribed mass


- dark staining area an= abnormal


--> increased N:C ratio


--> enlarged nucleii

What kind of neoplasm and its abnormalities?

What kind of neoplasm and its abnormalities?

Lyomyosarcoma


Malignant- not well circumscribed


- dark staining area = abnormal


--> pleomorphic nucleii


--> increase N:C ratio


--> hyperchromasia

What kind of neoplasm is it and its abnormalities?

What kind of neoplasm is it and its abnormalities?

mets from lyomyosarcoma in lung-alveolar spaces


--> loss of alveolar spaces


--> some desmoplasia (collagen formation)


-->pleomorphic and some cigar shaped nuclei


--> tumour giant cells (where mitosis isn't occurring)


--> loss of architecture of alveoli

What kind of neoplasm is it and its abnormalities?

What kind of neoplasm is it and its abnormalities?

adenocarcinoma- purple area abnormal of a colon (invades basement membrane)


--> loss of cell polarity


--> crowding


--> hyperchromasia


--> pleomorphism


--> fewer goblet cells


--> less differentiated


--> mucinous lakes in glands, irregular borders

What kind of neoplasm is it and its abnormalities?

What kind of neoplasm is it and its abnormalities?

polyp- adenoma (benign)


--> still forming glands- well differentiated


--> loss of polarity


--> cell crowding


--> fewer goblet cells


--> some mitosis


-->non invasive- hasn't passed submucosa/muscularis mucosa

What kind of neoplasm is it and its abnormalities?

What kind of neoplasm is it and its abnormalities?

Carcinoma In situ of trachea/bronchus


--> metaplasia caused by smoking


ciliated psuedostrat columnar => strat sqamous


--> mitosis and large nuclei in epithelium


-->island of strat squamous (may have invaded)


--> inflammatory cells and haemorrhage




Early signs of carcinoma = carcinoma in situ





What kind of neoplasm is it and its abnormalities?

What kind of neoplasm is it and its abnormalities?

invasive squamous cell carcinoma in bronchioles


--> nest and islands of cells


--> keratin pearls (very eosinophilic)


--> prickle cells with intracellular bridges



What kind of neoplasm is it and its abnormalities?

What kind of neoplasm is it and its abnormalities?

well circumscribed lesion- benign with glandular component


-tissue in between glands are abnormal


--> strands of collagen - benign neoplasm of fibroblasts

What kind of neoplasm is it and its abnormalities?

What kind of neoplasm is it and its abnormalities?

abnormal- pale purple area = adenocarcinoma of pancreas


--> irregular glands


--> abnormal nucleii


--> crowding


--> hyperchromasia


-->pleomorphic nuclei


--> prominent nucleoli


--> mitosis