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9 Cards in this Set
- Front
- Back
- 3rd side (hint)
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What is the best-known trade name for furosemide?
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Lasix
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The name Lasix comes from the implication that the relatively short-acting medication "lasts six hours".
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What is the functional class of furosemide?
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Loop diuretic
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Other loop diuretics include bumetanide (Bumex), torasemide (Demadex) and etacrynic acid (Edecrin).
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What is the mechanism of action of furosemide?
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Rapid-acting potent loop diuretic that inhibits sodium and chloride reabsorption in the nephron’s loop of Henle. Additionally, its vasodilatory properties reduce cardiac preload.
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The loop of Henle runs from the proximal convoluted tubule to the distal convoluted tubule.
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What are the listed indications for furosemide?
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- CHF
- Acute Pulmonary Edema |
Furosemide is also used to treat cerebral edema. It is also (legally) used in racehorses to help prevent exercise induced pulmonary hemorrhage (EIPH).
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What are the listed contraindications for furosemide?
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- Hypersensitivity
- Hypotension - Dehydration - Electrolyte depletion |
Furosemide is a sulfonamide and therefore may be contraindicated in patients with sulfa allergies
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What are the listed precautions for furosemide?
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- Usage in pregnancy should be limited to life-threatening situations as furosemide may cause fetal abnormalities
- Protect from light - Renal or hepatic insufficiencies |
Furosemide can worsen gout and is passed in breast milk. Also, in patients susceptible to urinary retention, acute urinary retention may occur, which is a medical emergency.
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What are the listed side effects for furosemide?
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- Hypotension
- Dizziness - Chest pain - Dry mouth - Hypochloremia - Hypokalemia - Hyponatremia - Hypomagnesemia - Hypocalcemia - N/V - Ototoxicity (tinnitus if pushed too rapidly) - Hyperglycemia |
Lasix can cause kidney stones or calcium deposits in the kidneys of premature infants
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What are the listed interactions for furosemide?
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- Digitalis
- Lithium toxicity |
Lasix should not be combined with aminoglycoside antibiotics unless absolutely necessary as this can increase the chance of permanent hearing loss.
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What is the dosage and route of furosemide?
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- 0.5-1mg/kg slow IVP over 1-2 minutes
- General dosing is 40-120mg slow IVP |
Dose selection for the elderly patient should be cautious, usually starting at the low end of the dosing range
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