Naplex Review Chapter 44 Iv Drugs, Fluids, And Antidotes

Front 1

drugs known to have leaching issues
(DEHP from PVC bags absorb into the medicine)

Back 1

tacrolimus, temsirolimus, teniposide, "taxel" class

Front 2

drugs with sorption problems
(medicine goes into the pvc bag-reducing conc of med)

Back 2

amiodarone, carmustine, lorazepam, nitroglycerin and reg insulin

Front 3

whats a crystalloid

Back 3

solution with sodium and electrolytes added
think NS or lactated ringers

Front 4

how should hypertonic solutions (crystalloid ) be admin

Back 4

thru central line

Front 5

what is a colloid
examples

Back 5

fluid used to increase osmotic pressure
albumin 5%, dextran, and hetastarch

Front 6

dobutamine
MOA
preferred use in...

Back 6

b-agonist, causing increase in contractility, Cardiac Output and increased HR

used in cardiogenic shock

Front 7

milirone
MOA

Back 7

PDE inihibitor in HR tissues= vasodilation and ionotropic effects

Front 8

DopAmine
MOA

Back 8

low doses-dopamine receptor

med- b receptor

high doses- alpha receptor

Front 9

epinephrine
brand name?
MOA

Back 9

adrenaline

B at low doses, alpha at higher doses

Front 10

norepinephrine (NE)
brand
MOA
preferred use in..

Back 10

levophed
B and alpha activity, incr contractility, HR, and vasoconstriction
alpha effects >B
used in septic shock

Front 11

what is extravasation

Back 11

leakage of IV vasopressors /ionotropes into surrounding tissues= tissue damage and necrosis

Front 12

if NE extravasation, us what

Back 12

phentolamine (regitine)- alpha blocker

Front 13

lorazepam
brand

Back 13

Ativan and lorazepam intensol
mix in d5W only

used in ICU sedation

Front 14

diprivan
generic name?
SE
Formulation
do not use what when administering

Back 14

propofol
SE- green urine
comes as LIPID EMULSION
do not admin with <5 micron filter

Front 15

precedex
gen name?
MOA
how long should it be admin?
use

Back 15

dexmedetomide
alpha 2 adrenergic agonist
do NOT give for >24H
ICU sedation

Front 16

morphine
whats the active metabolite

Back 16

morhine-6-glucuonide -accumulation in renal impairment- which causes a histamine release=hypotension

Front 17

fentanyl
benefit compared to morphine

Back 17

less hypotension b/c no histamine release

Front 18

dilaudid
gen name?

Back 18

hydromorphone

Front 19

how to calc anion gap

Back 19

Na - (Cl + HCO)
if >12 anion gap is metabolic acidosis

Front 20

VTE prophylaxis dose
UFH

Back 20

5,000 units SC BID- TID

Front 21

VTE prophylaxis dose
LMWH

if crcl <30?

Back 21

Enoxaparin 30mg SC BID or 40mg SC Daily

if CrCl <30ml/min give 30mg SC daily

Front 22

VTE prophylaxis dose
factor xa inhibitor

Back 22

fondaparinux 2.5mg SC daily-do not use <30ml/min pt

rivaroxaban 10mg Daiy-do not use in crcl<30

Front 23

inhaled hyperthermia can cause

how to tx

Back 23

severe hyperthermia

tx with dantrolene

Front 24

when initiating NMB's what should be done first

what should be on all NMB medications

Back 24

give adequate analgesia and sedation before starting NMB

NMBs should have a big sticker saying warning paralyzing agent

Front 25

nimbex
gen name
MOA

Back 25

cisatracurium

non-depolarizing NMB, short t1/2

Front 26

vecuronium
elimination?

Back 26

can accumulate in renal or hepatic dysfunction

so both

Front 27

what are hemostatic meds-what do they do and generally how?

Back 27

stop blood loss, by causing clots- generally inhibit plasminogen or conversion to plasmin

Front 28

what hemotatic med is fda approved for heavy menstrual bleeding

Back 28

tranexamic acid

Front 29

what is novoSeven RT
HOW does it work

BBW

Back 29

recombinant factor VIIa

activates extrinsic path- increasing prothrombin to thrombin

BBW- cotting risk, umm durrr

Front 30

thrombin in bandages
name the meds?

Back 30

thrombin-JMI- from cow, diseases
evicel-human, but a few diseases possible
recothron- recombinant -best cause no risk of disease

Front 31

fibrin sealants
meds
how do they work

Back 31

tisseel, evicel
contain fibrinogen and thrombin

thrombin converts fibrinogen to fibrin=clots

Front 32

ivig name

Back 32

basically anything w gamma or gam in name

Front 33

whats contraindicated in IVIG meds

Back 33

pts with renal damage

Front 34

whih stabilizers do not increase BS

Back 34

sorbitol
maltose- from corn, watch in corn allergy
glycine

Front 35

furosemide
iv to po ratio

Back 35

1:2 iv to po
store at room temp
do not dispense if yellow

Front 36

lebothryoxine
iv:PO

Back 36

1:2
IV is 50% of PO dose

Front 37

which meds are 1:1 iv to po

Back 37

metronidazole
Bactrim
phenytoin

Front 38

photosensitive IV drugs

Back 38

amiodarone
ampho
ceftriax
cipro
doxy
fentanyl
furosemide
levyothyroxine
linezolid
metronidazole
bactrim

Front 39

trissell lists what

Back 39

IV Meds in 4 types: sol compatablity, additive compat., y site compt, and drugs in syringe compat