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33 Cards in this Set
- Front
- Back
Name for Classifications of antiarrhythmics?
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vaughan-williams
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vaughan-williams class for quinidine?
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Ia
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vaughan-williams class for procainamide
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Ia
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vaughan-williams class for disopyramide
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Ia
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vaughan-williams class for lidocaine
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Ib
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vaughan-williams class for mexiletine
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ib
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vaughan-williams class for flecainide
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Ic
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vaughan-williams class for propafenone
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Ic
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vaughan-williams class for beta blockers
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II
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vaughan-williams class for amiodarone
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III
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vaughan-williams class for dofetilide
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III
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vaughan-williams class for sotalol
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III
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vaughan-williams class for verapamil
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IV
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vaughan-williams class for diltiazem
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IV
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moa of vaughan-williams class ia drugs?
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block NA channels, decreasing conduction velocity, increasing refractory period, decreasing automaticity
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se of quinidine?
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diarrhea, stomach cramping, cinchonism (tinnitus, blurred vision, HA, N, hearing loss)
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what is the metabolite of procainamide?
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n-acetyl procainamide (NAPA); renally eliminated; active metabolite
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black box on procainamide?
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blood dyscarasias (agranulocytosis) and drug induced lupus
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moa of vaughan-williams class ib?
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block NA channels, little effect on conduction velocity, decrease refractory period, decrease automaticity
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moa of vaughan-williams class ic?
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block na channels, significantly decrease conduction velocity, little effect on refractory period, decrease automaticity
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moa vaughan-williams class II?
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block beta recceptors and indirectly block calcium channels
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moa vaughan-williams class III?
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block K channels, no change on conduction velocity, significant increase in refractory period, no change in automaticity
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amiodarone infusions longer than 2 h must be admin how?
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in non-polyvinyl chloride container such as glass
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SEs of amiodarone?
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hypotension (IV), bradycardia, hypothyroidism/hyperthyroidism (more hypo), increase in LFTs, corneal microdeposits, optic neuritis, pulmonary fibrosis, ataxia, dizziness, tremor, photosensitivity, slate blue skin discoloration, insomnia
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preg cat amiodarone?
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D
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SEs of dronedarone?
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hepatic failure, renal failure, diarrhea, n, hypokalemia, hypomagnesemia, incr scr
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Betapace sub for betapace af?
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no
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moa of vaughan-williams class iv?
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block calcium channels
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moa of adenosine?
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decreases conduction through av node restoring normal sinus rhythm
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moa of digoxin?
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causes direct av node suppression, increasing refractory period and decreasing conduction velocity. has positive inotropic effect, enhance vagal tone, and derease ventircular rate to fast atrial arrhythmias
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indication for adenosine?
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paroxysmal supraventricular tachycardia (not for converting afib/aflutter or ventricular tachycardia)
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therapeutic range for digoxin for afib?
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0.8-2.0ng/ml
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s/sx of digoxin toxicity?
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n/v, loss of appetite, bradycardia, blurred vision, yellow vision, ab pain, confusion , delirium, prolonged pr interval, accelerated juntional rhythm, bidirectional ventricular tachycardia
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