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14 Cards in this Set
- Front
- Back
General characteristics of Mycoplasma
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Pleomorphic, NO CELL WALL
resistant to cell wall antibiotics (penicillins, cephalosporins) unable to Gram Stain slow grow, fastidious, aerobes or facultative anaerobes |
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What are L-forms?
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Cell wall deficient bacteria that arise from environmental stress. They are NOT mycoplasma
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Morphology of Mycoplasma
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many forms: spherical, pear-shaped, filamentous
0.2 to 0.8 um in diameter stain w/ ACRIDINE ORANGE Dienes stain for observing colonies Gliding motility on liquid covered surfaces |
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Cultivating Mycoplasma
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Very sensitive to desiccation
culture media: beef extract, horse serum, yeast extract w/ nucleic acids. Horse serum for cholesterol needed for sterols in membrane 1-6 hr generation time fried egg appearance, very small |
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Characteristics of Mycoplasma pneumoniae
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Primary atypical pneumonia
upper/lower respiratory pathogen, NOT commensal walking pneumonia: close contact areas (college, barracks) Dx formerly from cold agglutinins, now PCR & Serology |
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Characteristics of Mycoplasma hominis
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Colonizes genital tract of 1/2 healthy adults
Causes upper genitourinary tract infection in females: salpingitis, pyelonephritis, PID, postpartum fever |
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Characteristics of Ureaplasma urealyticum
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Colonize male/female gential tracts
Hard to know disease role - high carrier state in sexually active Non-gonococcal urethritis in men and upper genitourinary tract infection in women Assoc w/ reprod disorders, low birthweight w/ respiratory disease found in spinal fluid in infants |
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Characteristics of Chlamydiaceae
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resemble gnr
obligate intracellular parasites (can't make ATP) prefer columnar epithelia lining mucous membranes cultivated in susceptible tissue unique replication cycle |
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Characteristics of Chlamydia psittaci
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Psittacosis, parrot fever, ornithosis
found in wild birds treat w/ erythromycin, tetracycline |
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Characteristics of Chlamydia trachomatis
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3 Disease states:
1- conjunctivitis 2- Lymphogranuloma venereum 3- urethritis, PID, infertility, premature birth, cervical infection ID'd by Serology, DFA, PCR |
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Characteristics of Chlamydia pneumoniae
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aka TWAR / a cause of pneumonia
common among students pharyngitis followed by flu-like lower respiratory symptoms possible involvement in Coronary artery disease, asthma ID: serology, HL, PCR |
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Characteristics of Rickettsiae
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Gram NEGATIVe, obligate intracellular parasites
most can't be cultivated on ordinary media: need hen eggs, lab animals or cell culture Arthropod vectors, xcept in Q fever RMSF 90% of rickettsial disease in US |
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Characteristics of Coxiella burnetti
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Q fever, recovered from urine, feces, milk of animals & ticks.
can form endospore single organism is pathogenic Usually manifested as pneumonia ID: complement fixation treated by tetracycline |
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Characteristics of Rickettsia
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systemic disease, fever, rash, chills
ID by serology RMSP = R. rickettsii Murine Typhus = R. typhi |