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38 Cards in this Set
- Front
- Back
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Mycoplasma respiratory dz source & transmission |
infections contagious source = infected animal transmission = aerosols/direct contact |
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Mycoplasma resp. dz how does it cause dz |
superficial mucosal infection - replication - disruption of mucociliary clearance mechanism - persist on lumen - lymphoid hyperplasia |
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Mycoplasma resp. dz clinical signs |
increased mucous production destruction of cilia fluid in lungs |
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M. hyopneumoniae "Enzootic pneumonia of pigs" |
most important respiratory infection in swine |
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M. hyopneumoniae clinical signs |
cough retarded growth necropsy - lung lobes are purple/gray |
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M. hyopneumoniae extreme range severity |
dependent on air quality |
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M. hyopneumoniae diagnosis |
symptoms, slaughter checks ELISA, PCR |
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M. hyopneumoniae treatment |
antibiotics "all-in all-out" vaccine - doesn't prevent infection tho |
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M. gallisepticum species |
birds |
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M. gallisepticum clinical signs (chickens, turkeys, finch) |
chickens - chronic respiratory dz (cough, nasal discharge) turkey - infectious sinusitis (nasal discharge with foaming eye secretions) finch - conjunctivitis |
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M. gallisepticum diagnosis |
serologic testing |
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M. gallisepticum treatment |
certified MG free replacement stock vaccination = spray induces local immunity |
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M. pulmonis |
lab rats and mice chronic infection of airway |
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Mycoplasmas of cattle |
M bovis most pathogenic and virulent in US clinical diseases - respiratory, mastitis, otitis media, polyarthritis |
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Contagious bovine pleuropnemonia |
M. mycoides mycoides severe fibrinous pleuropneumonia seen in Africa/Middle East |
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BRDC 2 types |
shipping fever - beef Enzootic pneumonia of calves - dairy M. bovis plays major role |
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BRDC pathogenesis |
young cattle grouped together rapid circulation of M. bovis or viruses immunosuppression occurs - impairment of alveolar macrophage function - damage to mucociliary clearance - inflammation occurs - invasion of LRI |
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M. bovis Respiratory Dz source |
infected animal |
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M. bovis Respiratory Dz transmission |
aerosols & direct contact |
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M. bovis Respiratory Dz how does it cause disease |
superficial mucosal infection - delayed innate immune response - replication and invasion into tissues causes tissue damage and inflammation. necrotic lesions, dissemination, sequelae (otitis, polyarthritis, mastitis) LARGLY IMMUNE MEDIATED PATHOLOGY |
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M. bovis Respiratory Dz clinical signs |
necrotic lesions, microabscess formation from neutrophils, increased mucous production, fluid in lungs |
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M. bovis Respiratory Dz where to sample from |
nasal swabs transtracheal wash aspirate of fluid from joint/pleural cavity necropsy lung tissue |
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Otitis media differentials |
M. bovis Pasteurella multocida Arcanobacterium pyogenes |
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Otitis media pathogenesis |
initial respiratory infection disseminates via ascending or bacteremia abscess forms in eustachian tube |
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Should we vaccinate against mycoplasma |
no - does more harm than good |
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M. bovis Respiratory Dz diagnosis |
culture, PCR |
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M. bovis Respiratory Dz treatment |
antibiotics - NOT PENICILLIN THO |
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M. bovis Respiratory Dz prognosis |
mortality rate is low |
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M. bovis Respiratory Dz prevention |
closed herd |
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M. bovis Respiratory Dz is it zoonotic? |
no |
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M. bovis mastitis characteristic combo of clinical signs |
multiple quarters affected (hematogenous) no response to antibiotics stoppage of milk production - agalactia |
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M. bovis mastitis transmission |
contagious - enters via carrier 2 types - mammary, respiratory calf infections - contact with respiratory carrier, consumption of milk, may become reservoir mammary carriers will be persistent carriers for life!! |
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M. bovis mastitis treatment |
cull affected animals prevent with closed herd |
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Mycoplasma pathogens of swine |
M. hyopneumoniae M. hyorhinis - pneumonia M. hyosynoviae - arthritis |
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M. hyopneumoniae common features |
persist in URT & tonsils retarded growth = major problem treated with antibiotics |
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Mycoplasma in avians typical clinical presentations |
arthritis infertile respiratory disease conjunctivitis |
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Mycoplasma in dogs Typical associations |
Infertile pneumonia infections of GI, urinary tract |
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Mycoplasma in cats Mycoplasma felis |
Upper respiratory disease and conjunctivitis infertile |
