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43 Cards in this Set
- Front
- Back
opoid for pain, cough suppression
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dextromethorphan
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opoid for diaarhea
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loperamid and diphenoxylate
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toxicity includes respiratory depression, constipation, miosis
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opoid analgesics
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inhibits phopholipase a2
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coricosteroids
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inhibits lipoxygenase
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zileuton
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inhibits secretions of leukotrienes
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zafirlukast
montelukast |
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inhibits cox
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nsaids
acetominophen cox-2 inhibitors |
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pg that decreases platelet aggregation and tone
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PGI
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pg that increases platelet addregagion and vascular tone
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thromboxane
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pg that increases uterine tone and decreases vascular tone
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pge, pgf
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close pda
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indomethacin
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cox found in inflammatory cells that mediates inflammation and pain
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cox-2
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cox that maintains gastric mucosa
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cox-1
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toxicity includes hepatic necrosis, depletion of glutathione
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acetominophen
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anicdote for acetominaphen and action
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n-acetylcystein- regenerates glutathione
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gout treatment that inhibits xanthine oxidase
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allopurinol
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gout treatment that inhibits tubular reabsorption of uric acid
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probenecid
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gout treatment that depolymerizes microtubules
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colchicine
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gout treatment that inhibits secretion of penicillin
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probenecid
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use in lymphoma to prevent "tumor-lysis syndrome"
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allopurinol
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tnf receptor that binds tnf alpha
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etanercept
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used for RA, psoriasis, AS
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etanercept
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tnf alpha antibody
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infliximab
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used for chron's, ra, as
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infliximab
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inhibits calcineurin
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cyclosporine and tacrolimus
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suppresses organ rejection after transplantation
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cyclosporine
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potent immunosuppressive used in organ transplant recipients
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tacrolimus
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predisposes to viral infections and lymphomas
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cyclosporine
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to prevent cyclosporine nephrotoxicity
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mannitol diuresis
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toxicities are nephrotoxicity, peripheral neuropathy, hypertension, pleural effusion, hyperglycemia
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tacrolimus
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used with kidney transplantation and autoimmune disorders
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azathioprine
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metabolized by xanthine oxidase
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azathioprine
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6mercaptopurine derivative toxic to proliferating lymphocytes
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azathioprine
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cytokine used for renal cell ca and metastatic melanoma
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aldesleukin (interleukin-2)
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recombinant il-2
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aldesleukin
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recombinant erythropoiein
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epoeitin - for anemias, especially in renal failure
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recombinant granulocyte-csf
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filgastrim, sargramostim - to recover bm
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recombinant cytokines used for hep b and c, kaposi's, leukemia, and malignant melanoma
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alpha interferon
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recombinant cytokine for multiple sclerosis
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beta interferon
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cytokine used for chronic granulomatous disease
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gamma interferon
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cytokine to treat thrombocytopenia
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oprelvekin (il-11) and thrombopoietin
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cytokine used for chronic granulomatous disease
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gamma interferon
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cytokine to treat thrombocytopenia
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oprelvekin (il-11) and thrombopoietin
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