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5 Cards in this Set
- Front
- Back
Prevents paracellular movement of solutes; composed of claudins and occludins |
Tight junction (zone occludens) |
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Below tight junction, forms "belt" connecting actin cytoskeletons of adjacent cells with CADherins (Ca2+ dependent Adhesion proteins). Loss of E-cadherin = metastasis. |
Adherens junction (Zonula adherens) |
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Structural support via keratin interactions. Autoantibodies => pemphigus vulgaris. |
Desmosome (macula adherens) |
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Channel protons called connexons permit electrical and chemical communication between cells. |
Gap junction |
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Connects keratin in basal cells to underlying basement membrane. Autoantibodies => bullous pemphigoid. |
Hemidesmosome |