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9 Cards in this Set
- Front
- Back
MS - DEFINITION
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Multiple episodes of CNS dysfunction separated in time and space Cannot be due to anything else 2 attacks needed for diagnosis |
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MS - PATTERNS
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Primary Progressive PRMS - primary but with some relapses |
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OPTIC NEURITIS
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Can lead to atrophy Good prognosis for sight |
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TRANSVERSE MYELITIS
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UMN weakness below level and numbness at level; also sphincter disturbances if involved |
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BRAINSTEM ATTACKS |
Diplopia, ataxia, dysphagia, palsies, vertigo etc Internuclear Opthalmoplegia: on lateral movement abducting eye has nystagmus and adducting eye lags behind |
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MS - PAROXYSMAL SYMPTOMS
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TGN Tonic spasms Epilepsy |
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LHERMITTE'S
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Waves of parasthaesiae in limbs when stretched due to spinal cord scarring
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UTHOFF'S |
Visual problems with increased body temperature due to previous optic neuritis
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MS - MANAGEMENT |
Aims to reduce early inflammation and regression; in relapses do nothing or give steroids 1) Interferons; flu, capillary leak syndrome 2) Teriflunomide; not in pregnancy; HZV infections 3) Dimethyl fumarate; cytotoxic 4) "mabs"; potential cure but cause autoimmune diseases |