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14 Cards in this Set
- Front
- Back
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What is the antidote for a patient who was overdoes on acetaminophen?
What organ are you trying to save? |
Acetylcysteine
Liver |
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What NSAID is unique b/c it irreversibly inhibits cyclooxygenase?
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Aspirin
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What drug is unique in that it specifically inhibits COX2?
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Celecoxib
Spares COX1 which helps maintain the gastric mucosa |
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What drug is used instead of aspirin to prevent Reye's syndrome in children with viral infections?
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Acetaminophen
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Does Diabetes cause hypo or hyperkalemia?
How? |
Diabetic Ketoacidosis -> Hyperkalemia
Hyperglycemia increases plasma osmolality and dehydrates the cell, which causes K to leave the cell and enter the plasma |
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What 4 drugs block the collecting duct apical sodium channel, thus decreasing the gradient for potassium secretion -> hyperkalemia?
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Amiloride
Triamterene Trimethoprim Pentamidine |
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How does acute hyperkalemia cause depolarization?
How does chronic hyperkalemia cause repolarization? |
Increasing Na conductance = depolarization
Increasing K conductance = repolarization |
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What is the characteristic ECG abnormality found in acute hyperkalemia?
How does this happen? |
T wave amplitude that is as big as the QRS amplitude
Occurs secondary to the accelerated rate of repolarization |
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True or False
A normal ECG DOES rule out the presence of severe chronic hyperkalemia? |
False
ECG abnormality is characteristic of acute hyperkalemia, but may or may not also be present in chronic hyperkalemia |
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What medication might be useful to treat hyperkalemia?
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Insulin
Beta agonist - like albuterol |
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True or False
Hypoaldosteronism = Hyperkalemia |
True
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What two drugs are known to cause impaired aldosterone synthesis?
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Heparin
Ketoconazole |
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When using opoids tolerance does not develop to what two side effects?
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Constipating effects
Mitotic actions |
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What drug is used as a maintenance drug in treatment programs for opioid addicts, which with a single dose will block the effects of heroin for up to 48 hrs?
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Naltrexone
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