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26 Cards in this Set
- Front
- Back
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Morphine Other Names
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Duramorph,
Roxanol, MS-Contin |
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Morphine Class-Pharmacologic
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Opioid
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Morphine Class-Therapeutic
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Narcotic analgesic
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Morphine Mechanism of Action
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Powerful CNS depressant. It also increases the capacity of the venous circulation, pooling blood and decreasing blood return to the heart, thereby reducing myocardial oxygen demand. Also decreases systemic vascular resistance.
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Morphine Therapeutic Benefit
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Relieves pain caused by cardiac ischemia or trauma
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Morphine Indications for Use
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Chest pain with ACS unresponsive to nitrates.
Pain management analgesia in burns, & trauma |
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Morphine Contraindications
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Hypersensitivity
Hypotension Respiratory depression Head injury Undiagnosed abdominal pain. Patients taking depressant drugs. |
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Morphine Precautions
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Administer slowly!
May cause respiratory depression (SpO2 <95%) May cause hypotension in volume-depleted patients. (SBP <100 for adults, SBP<70 + 2(age in years/ for children <14 yo). Use with caution in right ventricular infraction. Reduce dose in patients >65 yo |
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Morphine Route & Dosage
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Adult: 2-5 mg IV (0.05mg/kg), may repeat dose every 5 minutes until maximum of 0.2 mg/kg. 5-20 mg SC or IM every 4 hours prn.
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Morphine Side Effects
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CNS: Confusion, sedation, headache, seizures, euphoria, somnolence, light headness, syncope
CV: Hypotension, bradycardia, tachycardia, hypertension RESP: Respiratory depression, apnea GI: Nausea, vomiting, constipation SKIN: Rashes, pruritus, flushing EYES: Dry eyes, blurred vision |
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Morphine Drug Interactions
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Effects may be reversed with narcan (0.4-2mg IV).
Additive CNS depression may occur when morphine is used with alcohol, antihistamines, sedative/hypnotics, antidepressants, barbiturates. |
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Morphine Protocols
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PA ALS
6003-1-2, 6071- 1-4 |
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Morphine
Onset Peak Duration |
Onset: 5 min IV, 10-30 IM or SC
Peak: 20 min IV, 30-60 min IM or 50-90 min SC Duration: 4-5 hr IV, SC or IM |
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Narcan Drug Name
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Naloxone
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Narcan Class-Pharmacologic:
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Narcotic antagonist
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Class-Therapeutic: Narcan
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Narcotic antagonist
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Narcan Mechanism of Action
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Competes with narcotic drugs opiate receptors in the CNS. This competitive action displaces narcotic analgesics from their receptor sites, blocking their effects, which include CNS depression and respiratory depression.
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Narcan Therapeutic Benefit
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Reverses the effects of narcotics
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Narcan Indications for Use
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Treat symptomatic narcotic overdose. Also can be used as a diagnostic tool in a coma of unknown origin.
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Narcan Contraindications
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Hypersensitivity
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Narcan Precautions
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Use in cautions in administering to patients with supraventricular arrhythmias, head injury, increased cranial pressure. Narcan may also cause seizures so use caution in administering it to patients with convulsive disorders.
Larger doses of narcan can precipitate opiate withdrawl syndrome with the potential for violent or combative patient behavior. |
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Narcan Route & Dosage
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Adults: 0.4 mg IV or IO or 2 mg IM or Intranasal. May repeat every 2-3 minutes in 0.4 mg increments to a total of 2 mg.
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Narcan Side Effects
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CNS: Tremors, seizures
RESP: Pulmonary edema CV: Ventricular tachycardia, ventricular fibrillation, hypotension or hypertension. GI: Nausea & vomiting Skin: Diaphoresis |
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Narcan Drug Interactions
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Propoxyphene and dextromethorphan require higher doses of narcan.
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Narcan Protocols
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PA ALS 7002A
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Narcan
Onset, peak, duration |
Onset: 1-2 min IV, 2-5 min IM or SC
Peak: 5-15 min IV, SC or IM Duration: Variable all routes |
