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4 Cards in this Set

  • Front
  • Back
what two key substrates are required for the synthesis of DNA to proceed?
1) the four deoxynucleoside triphosphates
2) a primer:template junction
what are the four deoxynucleoside triphosphates?
dGTP, dATP, dCTP, dTTP
what is a primer:template junction?
a particular arrangement of ssDNA and dsDNA
what are the two key components of a primer:template junction and what are they responsible for?
1) the template provides the ssDNA that directs the addition of each complementary deoxynucleotide
2) the primer is complementary to the template (but shorter than it) and must have an exposed 3' OH adjacent to the single stranded region of the template