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15 Cards in this Set
- Front
- Back
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what are some characteristics of apoptosis?
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chrom. condensation
cell shrinkage preservation of organelles DNA fragmentation |
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What are some charactersitics of necrosis?
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nuclear swelling
disruption of organelles rupture of the cell and release of cellular contents |
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how is apoptosis useful in fetal development
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scults the embryonic form, develops the nervous system, eliminates self-reactive components
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how is apoptosis useful in adults
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stimulation of T-lymphocytes
responds to DNA damage on withdrawl of supporting hormmones of certain organs and tissues. |
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ced-3
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required for apoptosis in C. Elegans
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Ced-1
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leads to engulfment of dead cells
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ced-9
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programmed for cells to live
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ced-4
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protein programmed for cell death
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ced-9 and Bcl-2 are homologous, and do...
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they are the cell regulators, they both function to suppress apoptosis in the presence of trophic factors
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trophic factor
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signals in our cells for them to stay alive
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ced-4 and Apaf-1 are homolougous, what do they do ?
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they are adaptors
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Ced-3, Caspase 9 and capase 3 are homologous, what do they do?
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they are effectors
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ced-3 is known as?
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the executioner
is a cysteine protease |
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Caspase 1 (formerly known as ICE) breaks up into 2 parts called?
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p20 and p10
(p20:p10)2 <- functional enzyme |
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how are proenzymes activated?
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proteolytic cleavage
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