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16 Cards in this Set

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  • Back

Definitions/terminology

Visible haematuria (VH) - macroscopic (red urine)




Non-visible haematuria (NVH) - Dipstick positive


- Symptomatic non-visible haematuria (s-NVH)


- Asymptomatic non-visible haematuria (a-NVH)

Causes - general

UTI, bladder tumours, urinary tract stones, urethritis, benign prostatic hypertrophy (BPH) and prostate cancer




5% aNVH have malignancy

Investigations

Plasma creatinine and estimated glomerular filtration rate (eGFR)




Urological referral




Nephrological referral once urological referral ruled out

Renal cancer overview

Classic triad of haematuria, loin pain and loin mass is not often seen now. Normally asymptomatic and diagnosed with US




Surgery

Renal stones overview

Renal calculi are formed when the urine is supersaturated with salt and minerals such as calcium oxalate




Sudden severe pain




CT scan




Generally pass spontaneously




Extracorporeal shock wave lithotripsy (ESWL)


Percutaneous nephrolithotomy (PCNL)


Ureteroscopy


Open surgery

Anatomy of urinary system overview

Kidneys - nephrons - waste products and uneeded water


Hormones - EPO, renin, Calcitriol (vit D absorption)


Ureters


Bladder


Prostate (in men)


Urethra

Suggests a renal origin

Hypertension, altered renal function tests, proteinuria, known previous renal problems, renal mass and glomerular red cells (red cells with irregular contours and shape) in the urine

Causes - infection

Cystitis, tuberculosis, prostatitis, urethritis, schistosomiasis, infective endocarditis

Causes - Tumour

Renal carcinoma, Wilms' tumour, carcinoma of the bladder, prostate cancer, urethral cancer or endometrial cancer.

Causes - Trauma

Rrenal tract trauma due to accidents, catheter or foreign body, prolonged severe exercise, rapid emptying of an overdistended bladder (eg, after catheterisation for acute retention)

Causes - inflammation

Glomerulonephritis, Henoch-Schönlein purpura, IgA nephropathy, Goodpasture's syndrome, polyarteritis, post-irradiation

Causes - Structural

Calculi (renal, bladder, ureteric), simple cysts, polycystic renal disease, congenital vascular anomalies

Causes - Haematological

Sickle cell disease, coagulation disorders, anticoagulation therapy.Surgery: invasive procedures to the prostate or bladder

Causes - Toxins

Sulfonamides, cyclophosphamide, non-steroidal anti-inflammatory drugs

NICE guidelines for cancer referral

Bladder or renal cancer: haematuria (visible and unexplained) either without UTI or that persists or recurs after successful treatment of UTI (patients aged 45 and over)




Bladder cancer: haematuria (non-visible and unexplained) with dysuria or raised white cell count on a blood test (patients aged 60 and over)

PSA test

Not sensitive or specific


Limited benefit of early intervention


Causes: Enlarged prostate, inflammation, UTI or cancer