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36 Cards in this Set

  • Front
  • Back
Clinical Immunology involves the study of what?
Ag and Ab reactions
a division of immunology focusedon detecting and measuring specific Abs that develop in blood?
Serology
What causes Abs to develop in blood?
exposure to a specific disease producing Ag
What is the immune response?
An Ab response to an Antigenic stimulus
Natural And Active
Produce Ab in response to infection
Natural and Artificial
Produce Ab in response to vaccine
Natural and Passive
Ab passed from Mom to baby
Artificial and Passive
Ab by infusion of Plasma
Cell mediated immunity involves link between what two cells?
T-lymphocytes and Phagocytic Cells
what lymphs are derived from the thymus and are present in 0-80% of circulating lymph?
T lymphocytes
How long do Mature T-lymphoctes survive for?
months or years
How much of the circulating lymph is B lymphocytes?
about 20%
where do B lymphocytes mature?
In Bone Marrow
What is the functions of B lymphocytes?
Ab production or Formation of Igs
how lond go B lymphocytes survive for?
a few days
What types of Specimens are tested in immunological studies in Lab?
Serum
Urine
Spinal Fluid
What happens when antigens are introduced into the body?
They cause the formation of Ab
What are the five classes of Ig?
IgG,IgM,IgA,IgD,IgE
which is the largest class of Ig?
IgM pentamer
which is the smallest class of Ig?
IgG monomer
T or F
Ig are not antibodies, they are there own structures?
False; they are antibodies
What happens when antigens are introduced into the body?
They cause the formation of Ab
What are the five classes of Ig?
IgG,IgM,IgA,IgD,IgE
which is the largest class of Ig?
IgM pentamer
which is the smallest class of Ig?
IgG monomer
T or F
Ig are not antibodies, they are there own structures?
False; they are antibodies
what type of Ab are derived from multiple clones of Ab producing cells?
Polyclonal Ab
what type of Ab are derived from a single clone of Ab producing cells?
Monoclonal Ab
When are polyclonal Ab's characteristically produced?
Infectious Disease
Why are Monoclonal antisera used in testing?
b/c of greater diagnostic precision
how long is required for immunity to develop?
about 2 weeks
when should blood be drawn when testing for infectious disease?
in the acute phase and then 2 weeks later in the convalescent phase
what is the Ab titer
The concentration, or amount of Ab
What is the Ig involed in the primary response and when?
IgG at about 10-14 days
when is the Ab titer the highest?
at about 20 days
Agglutination occurs only when Ag is in the form of what particles?
Bacteria, RBCs, and latex