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28 Cards in this Set
- Front
- Back
BMS is preferred of DES in these cases
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poor adherence to therapy, HR of bleeding separate indication for long term anticoagulation, anticipated surgery
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indications for CABG in the setting of NSTEMI
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failed PCI and undergoing surgery for septal or free wall rupture. coronary anatomy not amenable to PCI and have high-risk features (ongoing or recurrent ischemia, cardiogenic shock, or severe heart failure
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Only two dihydropyridine calcium channel blockers found in to have neutral effects on mortality in heart failure
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amlodipine and felodipine
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the only oral anticoagulant indicated for the prevention of thrombosis of mechanical prosthetic valves
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warfarin
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additional indications for apixaban, rivaroxaban, dabigatran
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Apixaban and rivaroxaban for stroke and blood clot prophylaxis in atrial fibrillation; Dabigatran for treatment of atrial fibrillation
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what is imiquimod
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topical medication occasionally used to treat lentigo maligna when surgery is not an option
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when to proceed with sentinel lymph node biopsy in malignant melanoma
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histologic features such as elevated mitotic rate or presence of ulceration
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use of this drug reduces the number of squamous cell carcinomas in transplant patients on immunosuppression
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sirolimus / everolimus (whereas tacrolimus and cyclosporine increases the risk)
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moderate to severe psoriasis - need to screen for?
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dyslipidemia, hypertension, obesity, and diabetes mellitus. (these patients are at increased risk of cardiovascular disease)
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Young female patient with IBD flare and no other risk factors for DVT should still be placed on DVT prophylaxis
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owing to the high risk of VTE (3-fold without exacerbation, 15-fold with exacerbation.) Even with rectal bleeding, start VTE prophylaxis
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Hepatits C surveillance
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liver US every 6 months; AFP has no benefit
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rash is common with HCV treatment, how to manage this?
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if mild to moderate, emollients, antihistamines and topical steroids can be given; if severe, stop telapravir and continue interferon and ribavirin; if with SJS, then stop all antivirals
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Barrett's patient, endoscopy shows low grade dysplasia, what's next
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repeat EGD in 6 months with biopsies - surveillance
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Barrett's patient, endoscopy shows high grade dysplasia, what's next?
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endoscopic mucosal resection
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treatment for unprovoked DVT
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first episode - coumadin for 6 months, and based on WARFASA study, aspirin indefinitely, will reduce recurrence
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after AVR with a bioprosthetic valve, how long to given warfarin?
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6 months! not 3 months, according to a recent Danish study
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indications for Rivaroxaban
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prevention of stroke in Afib; prevention of DVT in ortho; treatment of DVT
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contraindications to Rivaroxaban
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liver or kidney injury, pregnancy, patients on HAART (lopinavir-ritonavir)
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advantages of Rivaroxaban
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oral, once daily dosing, no effect on AST/ALT, does not require monitoring
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why are aromatase inhibitors used only in postmenopausal?
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aromatase inhibitors block peripheral conversion of androgens to estrogen. there is concern that peripheral blockade may stimulate central gonadotropin production and lead to increased estrogen production by the ovaries in premenopausal patient
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how many years to give tamoxifen therapy in premenopausal patients with breast cancer?
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now it's 10 years
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Suggestive features of vasovagal syncope include any of the “3 Ps”: prodrome (lightheadedness, blurred vision, sweating, nausea), provocation (stress, micturition, dehydration), or posture (prolonged sitting or standing).
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cause
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Syncope accompanied by a neurologic prodrome (déjà vu and olfactory or visual hallucination), focal neurologic deficits (tongue biting, head or eye deviation, postevent confusion, postevent hemiparesis), or seizure risk factors (head trauma, meningitis, intracranial mass, illicit drug use) suggests seizure as the cause
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cause
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cardiogenic LOC often lacks a prodrome or can be preceded by subjective palpitations.
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cause
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Revised criteria define status epilepticus as persistent clinical or electroencephalographic seizure activity for greater than five minutes or recurrent seizure activity without interictal return to baseline
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cause
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In the out-of-hospital setting, intramuscular midazolam is effective in aborting status epilepticus, especially in persons with poor venous access.
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access
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Medical management is superior to angioplasty and stenting in treating atherosclerotic intracranial stenosis.
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Aggressive medical management consisted of lipid lowering, blood pressure management, aspirin, clopidogrel, and lifestyle modification
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FDA approved for the treatment of rheumatoid arthritis and can be administered in those with heart failure
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Abatacept
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