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19 Cards in this Set

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Define Cardiac Channelopathies?

conditions in which no morphologic abnormalities are obvious but the risk for SCD is increased

MC chaneelopathy?

Long QT

Incidence of long QT?

1 in 5000

cause of syncope in long QT syndrome?

Polymorphic VT

R/Fs for SCD in long QT syndrome?

a history of sudden cardiac arrest,

recent syncope, and

QTc interval greater than 500 msec.

cardiac arrest during sleep...dx?

long QT

cardiac arrest during sudden loud noise...dx?


cardiac arrest during exercise....which channelopathy?

long QT

Ix of ICD in Long QT syndrome?

1. strong F/H of SCD

2. Syncope while taking BB

3. VT while taking BB

4. h/o cardiac arrest

mainstay of treatment in long QT?


if still having VT or syncope, then ICD

arrhythmias in long Q?T vs short QT

Long QT = polymorphic VT/Torsades de pointes

Short QT = AF, polymorphic VT, VF

drug therapy for long QT and short QT?

Long QT = BB

Short QT = quinidine

define brugada syndrome?

Brugada syndrome is a pattern of 2 mm or greater J-point elevation, coved ST-segment elevation, and T-wave inversions in leads V1 to V3 with an increased risk of syncope, VF, and sudden cardiac arrest

Is brugada pattern in brugada syndrome patient spontaneous (detected on EKG) or intermittent (induced)---why is this question important

Those with spontaneous ECG findings are at a higher risk for cardiac events.

how to elicit brugada pattern in a brugada syndrome patient with Intermittent ECG findings?

infusion of a sodium channel blocker

brugada pattern can be seen in other conditions also, not only brugada syndrome?

1. fever

2. hypokalemia

3. hyperkalemia

4. TCAs

5. Cocaine

6. Alcohol

medical treatment of brugada?>

controversial...may be quinidine

3 causes of bidirectional VT?

Bidirectional ventricular tachycardia (BVT) is a rare ventricular dysrhythmia characterised by a beat-to-beat alternation of the frontal QRS axis.

1. digoxin toxicity (mcc)

2. Catacholiminergic polymorphic VT

3. herbal aconite poisoning

smoking cessation after MI is surely beneficial...in one cohort mortality in smokers after 3 years of quitting is equal to nonsmokers equivalents....question is are there any short term benefits of quitting after MI?

Yes; decrease progression of disease, decrease mortality, decrease hospital readmissions

benefits of cessation are seen early after cessation