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19 Cards in this Set
- Front
- Back
Define Cardiac Channelopathies? |
conditions in which no morphologic abnormalities are obvious but the risk for SCD is increased |
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MC chaneelopathy? |
Long QT |
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Incidence of long QT? |
1 in 5000 |
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cause of syncope in long QT syndrome? |
Polymorphic VT |
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R/Fs for SCD in long QT syndrome? |
a history of sudden cardiac arrest, recent syncope, and QTc interval greater than 500 msec. |
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cardiac arrest during sleep...dx? |
long QT |
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cardiac arrest during sudden loud noise...dx? |
LONG QT |
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cardiac arrest during exercise....which channelopathy? |
long QT |
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Ix of ICD in Long QT syndrome? |
1. strong F/H of SCD 2. Syncope while taking BB 3. VT while taking BB 4. h/o cardiac arrest |
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mainstay of treatment in long QT? |
BB... if still having VT or syncope, then ICD |
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arrhythmias in long Q?T vs short QT |
Long QT = polymorphic VT/Torsades de pointes Short QT = AF, polymorphic VT, VF |
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drug therapy for long QT and short QT? |
Long QT = BB Short QT = quinidine |
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define brugada syndrome? |
Brugada syndrome is a pattern of 2 mm or greater J-point elevation, coved ST-segment elevation, and T-wave inversions in leads V1 to V3 with an increased risk of syncope, VF, and sudden cardiac arrest |
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Is brugada pattern in brugada syndrome patient spontaneous (detected on EKG) or intermittent (induced)---why is this question important |
Those with spontaneous ECG findings are at a higher risk for cardiac events. |
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how to elicit brugada pattern in a brugada syndrome patient with Intermittent ECG findings? |
infusion of a sodium channel blocker |
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brugada pattern can be seen in other conditions also, not only brugada syndrome? |
1. fever 2. hypokalemia 3. hyperkalemia 4. TCAs 5. Cocaine 6. Alcohol |
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medical treatment of brugada?> |
controversial...may be quinidine |
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3 causes of bidirectional VT? |
Bidirectional ventricular tachycardia (BVT) is a rare ventricular dysrhythmia characterised by a beat-to-beat alternation of the frontal QRS axis. 1. digoxin toxicity (mcc) 2. Catacholiminergic polymorphic VT 3. herbal aconite poisoning |
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smoking cessation after MI is surely beneficial...in one cohort mortality in smokers after 3 years of quitting is equal to nonsmokers equivalents....question is are there any short term benefits of quitting after MI? |
Yes; decrease progression of disease, decrease mortality, decrease hospital readmissions benefits of cessation are seen early after cessation |