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40 Cards in this Set

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Machine that sucks blood to separate it for at least 1 hour

Apheresis machine

Red cell suspension

2 to 5 percent

2 to 3 min at 3200 rpm

Light spin

MCV

Mean cell Corpuscolar Value

MCH NV: 27 to 31

Mean cell corpuscular Hemoglobin

Deficiency in B12 and B 9


Nuclear maturation lags behind


Oval, Macrocyte


Pernicous, Anemia

Megaloblastic

Need for Hb synthesis


Cytoplasmic maturation lags behind


Microcytic and Hypochromic


Iron deficiency Anemia

Iron deficiency

DAT

Direct antihuman globulin test

IAT

Indirect antihuman globulin test

HTR occurs when blood transfused is wrong type

Hemolytic Transfusion Reaction

DIHA drug in vivo sensitization of cells

Drug induced nemolytic anemia

HDFN- when mother is rh negative and the baby is rh positive. But this only happens if its the second baby because the mother already developed anti bodies.

Hemolytic disease of the fetus and New born

P polychromatophilia


S spherocytes


T teardrop RBC


A acanthocytes


S schistocytes


H helmet cells


1+ if 1 to 5/ field


2 + if 6 to 10/ field


3+ if greater than 10

B bizzare shape rbc


E elliptocyte


B burr cell


S stomatocytes


T target cell


O ovalocytes


P poikilocytosis

1+ 3 to 10


2+ 11 to 20


3+ greater than 20

Rouleaux formation

1+ 3 to 4


2+ 5 to 10


3+ more than 10 numerous

Basophilic stippling


Sickle cell


Pappenheimer bodies


Howell jolly bodies.

Positive or negative

80f L

Microcytic anemia

80 to 100 fL

Normocytic

Greater than 100 fl

Macrocytic anemia

T- thalassemia- globin chain synthesis


A- anemia of chronic disease- fE sequestration


I- IDA (most common) heme synthesis


S- sederoblastic anemia


Bot I and S protophorphin synthesis defect.

Microcytic anemia problem wth HB

Aplastic anemia


Chronic live disease


Alcoholism


Large RBc


Membrane change- disruption of cholesterol to phospholipids

Non megaloblastic anemia

Vit b12 and b9 deficiency


Cause of impairment in DNA synthesis


parasite that feeds on vit B12



Megaloblastic

1. Primary hemostasis- vascular system amd platelets


2. Secondary hemostasis- coagulation factors

Stages of hemostasis

Primary hemostasis


1.vasoconstriction2. Platelet Adhesion 3. Platelet activation 4. Platelet secretion 5. Platelet Aggregation 6. Formation of platelet plug

Secondary hemostasis

1. Generation of thromboplastin


2. Conversion of prothrombin to thrombin


3. Conversion of fibrinogen to fibrin


Chart

Brain

Microglia

Bone

Osteoclasts

Heart and Vasculature

Heart Macrophage

Liver

Kupffer

Lungs

Alveolar

Adipose

Adiposw

Bone marrow

Bone marrow

Gut

Instestinal macrophages

Skin

Langerhans

Spleen

Marginal zone

10 ml 5% rbc


10000 ml x 0.05


=500 ml- rbc


10000- 500


9500 M- nss normal saline solution

Red cell suspension computation

Mcv formula

Mcv hct %/ rbc (x10 to the 12 power) L multiply by 10.

Mch formula

Mch= hg(g/dL)/RBC (x10 raise to 12 L)

MCHC formula

Hb= hb (g/dL)/ hct (%) multiply by 100