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24 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Ayman Innate... 1st or 2nd line of Defense.... Components |
1st
Mech barriers Ch Barriers Flushing action Bio factors
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Mech barriers .. Ex... Which sweep مسح org... MCQ Which act as trapping mech |
SCM -Intact Skin and Mucus -Cilia -Sticky Mucus
Cilia
Sticky Mucus |
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Flushing action طرد : Ex.... MCQ Which is imp in as Flushing agent in mouth w what its 2nd action.... Which expel يطرد Micro org and contaminated |
-Peristalsis movement of GIT - Flow rate of urine - Saliva - cough and sneezing
Saliva.... Vehicle for Chemicals (buffers w Enzymes)
Coughing and sneezing |
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Peristalsis movement of GIT prevents what... |
Colonization |
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Chemical barriers
MCQ Many Contains which factors... Ex... MCQ Which present in tears w nasal w saliva secretions.... MCQ Which present in Sweat w Sebaceous 2S |
Microbicidal
-LA w FA -Lysozymes
Lysozymes
LA w FA 2A |
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Bio factors (Normal Flora w Phagocytosis w NK w EFF Ptns)
Normal flora صاحب البيت :MCQ Prevents what.... BY |
Occupation of Colonized sites by pathogens
- Competition for essential لو هيقعد بأدبه - Production of Bacteriocines لو هيقل أدبه |
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MCQ Bacteriocines inhibitory or stimulatory |
Inhibitory |
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Phagocytosis - If circulating blood لو وصلو الدم so as -If Residing in tissues so as -Ayman MCQ F45 Phagocytic recognize microbes by w Extra MCQ this by ex w these recognize w not present in w ex... -MCQ in Summary : Steps : Ingestion of bacterium forming??? Which fuse with??? Forming??? |
Neu MO Neutrophils w monocytes
MAC DE MAC w Dendrites
Pattern Recognition Receptors PRR....Toll like receptors TLRs. .. PAMPs Pathogen asscociated molecular patterns... Mammalian cells... Lipopolysacchrides LPS w techoic acid
Phagosome.. Lysosomes... Phagolysosome |
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Non Oxi : MCQ Activated MAC produce which enzymes w as.... Oxi : -MCQ Cell uses molecular O2 to produce Reactive O2 as... -Are they Toxic... -MCQ Name of process w this involves Activation or Inactivation of Oxidase ... -VI :Another func of Oxidase enzyme is w this necessary for activation of w F45 eff on Outcome |
Proteolytic... Elastase
Superoxide ions w hydrogen peroxide w free hydroxyl radicals
Yes
Oxidative Burst... Activation
Induce Acidic PH ... Proteolytic enzymes.. ⬇️⬇️
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MAC MCQ - secrete.??? Cytokines... -Causes VD or VC w Recruitment of |
Pro-inflammatory
VD... Neutrophils |
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MCQ
Outcomes of Phagocytosis -Neutrophils action... -Which that Preserve useful info and able to present adaptive w they called... |
Destroy Phagocytosed completely
MAC w Dendrites.. APC |
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Ayman MCQ F45 Functions of Mac.. 3 func |
Cytokines Production Destroy Microbes (Phagocytosis) APC |
APC |
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Direct EC Killing by NK:... -It is effecient mech to defeat what - MCQ F45 Is it need prior sensitization? -Ayman NK are??? Lymphocytes w part of which response innate or Acquired... -Ayman NK kills cells that.... -When NK Release contents of their granules into space.. -Ayman MCQWhich granules Form transmemb Pores w followed by .. -MCQNK no longer express what .... -Ayman + by what ... -Ayman - By What... -Ayman Marker is -Ayman MCQ Secrete which Interferon |
Large particles which can not Phagocytosed عيل بارد
NO
Large Granular... Innate
- not express or altered self Ag (MHC) -Malignant w virally infected cells
Once activated
Perforin w Granzymes... Cell Death (Apoptosis)...
MHC I
IL2
All nucleated cells (MHC I)
CD16 w CD56... 6 w (5+1=6)
Gamma |
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Circulating eff ptn... 1)Complement : - Group of insoluble or soluble plasma ptn - MCQactive or inactive Form... -MCQ Once activated, it Enhances 2)Cytokines : -MCQ F4555 Allow for what -Control what... -Ex.... 3)Acute phase ptns : -Ayman Are Ptns inc when -Ayman As... -MCQ Can enhance Phagocytosis By... -Ayman MCQStimulate Activation of.. -MCQ What also considered Acute phase ptns |
Soluble
Inactive
Phagocytosis w Lysis of bacteria
IC communication
Func of Immune System
INF or IL
-Following infection (Liver response to cytokines)
-C Reactive ptn CRP (➕Phagocytosis) -Mannose binding ptn(➕complement Activation )
opsonins
complement
Fibrinogen |
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Interferons MCQ : -Types -Which Type secreted by Viral cells w provide Immunity to adjacent cells.. . -Which Type secreted by fibroblasts... -Which secreted by NK w T cells to Activate MAC and T Lymphocytes |
A w B w gamma
A
B
Gamma |
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-MCQ What are the 3 Major events in inflammation... -Acute inflammation Characterized by W MCQ Ex (Effects) |
VD ⬆️ Permeability Migration of WBC
Hotness w redness w swelling Pain w loss of function.. Acute Epiglottis (Swelling) w TD |
الLocal Signs اللي في الباثو |
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MCQ VD > ⬆️ or ⬇️ Blood Supply... ⬆️ Permeability > To allow... |
⬆️
Migration of WBC |
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Opsonization..Ayman MCQ Ex... MCQ F45 enhance |
Acute phase ptns C3b = complement Ch3 = IgG
Phagocytosis |
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MCQ Tissue damage induced by wound or invading Patho org... Is |
Inflammation |
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MCQ Ayman
Compare between innate w adaptive
-MCQ F45 Other name of innate -1st or 2nd line of Defense -Specificity -Memory -Magnitude (Response) مهمة فشخ -Comp -Time of Reaction |
-Rapid -Slow |
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Ways of Intracellular Killing of ingested micro org |
Oxi Killing Non Oxi Killing |
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Define Ayman مهم فشخ
-Substance recognized by Immune System -Substance induces IR -Substances has low MW w unable to induce IR by itself -Site on Ag (identical in CHO w Diff in Ptn) -Ags Sharing one or more epitopes |
-Ag
-Ig
-Hapten
-Epitopes (Ag determinant)
-Heterophil Ags (Cross Reactivity) |
مش اي حاجة كدا الIR تتعرف عليها |
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MCQ Of Define Ayman
-is all Ig are Ags -when Hapten make IR -Hetrophil Abs react with -Heterophils Ags : Pract App -Relation between Size and Non Self with Ig |
-Yes
-when bind with Carrier Ptn لما يمسك مع واحد مش باين عليه
-shared epitopes of hetrophil Ags
-Patho of Rheumatic Fever -Direct |
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MCQ F45 is innate w aq interact with each other |
Yes |
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