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10 Cards in this Set
- Front
- Back
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B Lymphocytes : Origin.. Maturation... Percent.. Sites.. Func |
BM
BM
30 %
Circulating Lymphocytes w 2ry lymphoid Organs
- Humoral Immunity (against EC w toxins) - APC |
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Ayman Diff between BCR and TCR
MCQ Formed of which Ig Structure (how many chains) MCQ Signaling Ag binding Site MCQ MHC present or not Secreted form |
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Ayman Activation of B Lymphocytes : -MCQ F45 Activated B cells called... -MCQ Class Acc to Ag |
Plasma cells
TD Thymus dependent Ag TI Thymus independent Ag |
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MCQ F45 Ayman
Comp between TI w TD
MCQ Structure or chemistry
%
AB Synthetic (Ig)
Memory (anamnsteic or booster response)
MCQ Which of them cross link BCR |
TI |
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-AYMAN TI : Ag binds with w result... - TD.. 1)AYMAN Ag binds with?? 2) MCQ what happened to Both inside B cell 3) what happen to Ag 4)MCQ presentation with which MHC. 5)MCQCo-stimulation occ between w lead to Production of 6)Ayman leading to B cells Poliferation and diff into 7)Ayman MCQ f45 interaction between CD40 (on B cell) w CD40 L (on T cell) requires for 8)formed at end |
BCR... +B cell
1)BCR 2)receptor mediated endocytosis 3)processed 4) II 5)CD28 (on T cell) w B7 (on B Cell)... cytokines 6)Plasma cells >AB 7) class switching of Ig 8) Memory B cells |
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MCQ Ayman
1ry w 2ry IR...
B CELL
Lag
Ab needed w Which Types of B Activation
Ab produced (Ig)
Ab Level |
Naive ناييف Memory
Long (4 to 7 d) Short (1 to 3)
TD w TI... High Conc عشان احس بيه TD only... Low Conc عارفه قبل كدا فا مش هحتاج كتير
IgM IgG
Low High |
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Ig : -Synonym of Ig -Simplest molecule isَ w formed of w bonded by.. -Light chains consists of how many VL w CL. - Heavy consists of how many VH w CH - MCQ F4555 Ig Classes distinguished by Which region -How many Types of Ig.. -MCQ F45 What responsible for Antigen-binding w it is Variable or Constant... - Crystallizable fragment which is w responsible for.... |
AB
Y Shaped... 4 Polypeptide chains....disulfide bonds
1 w 1
1 w 3 or 4
Constant of Heavy
5 MAGED.. IgM w IgA w IgG w IgD w IgE
Fab fragment (Epitope) ... Variable
Fc portion... 1)CH3 : Contain MAC w Neutrophils 2) CH2 : Contain Complement
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Ig classes MCQ f45 Ayman .... -Which one used in mucosal Immunity (1st line) w by w its Structure -1st AB secreted (IR) w its size w due to its size so inhibit w its Structure... -MCQ F45 The only cross placenta w so MCQ give fetus?? Immunity w its structure . .. -Which attack bacteria intravascular.. -Which attack bacteria extravascular... - IgG =... - IgD =... - MCQ F45 Which Type major role in Allergy w Parasitic... -MCQ F45 Main Ig in blood.. - Which Type in opsonization w ADCC... - The only Type Synthesized by fetus w so its presence = w powerful in ... -MCQ Types activate Complement -Structure -Most % -Highest MW -Longest 1/2 life -neutralize bacterial toxin -How many subclasses in IgG w IgA |
IgA(secretory).. . Coating org... Dimer(J chain) ...
IgM.. Large(Highest MW) .. Bacteremia... Pentamer (J chain)
IgG... Natural Passive.... Monomer (Y)
IgM
IgG
Memory (2ry IR)
BCR
IgE (Eosinophils)
IgG
IgG
IgM... Intrauterine infection... Agg w complement fixation
IgM اقوي w IgG
IgG : Monomer Y IgM : Pentamer (J chain) IgA : Dimer (J chain) IgE : Y IgD : Y
IgG then IgM=IgA
IgM عشان خماسي
IgG
IgG IgG : 4 IgA : 2 |
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MCQ AB func |
-Neutralization - Opsonization - Complement Activation - ADCC (AB dependent Cell mediated Cytotoxic) |
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1)Opsonization : - MCQ by which Ig 2)Complement Activation : -which pathway -MCQ which Ig 3)Ayman Classical ADCC : - MCQ mediated by -these cells have receptors for -IC or EC Killing of Ag -can kill |
IgG
Classical
IgG w IgM
NK.
Constant of IgG (fc gamma) EC Worms (IgE) |
