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12 Cards in this Set

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Ayman


-MCQ Type of Immune response


- MCQ Result in...


-Due to...


- MCQ 1ry or 2nd exposure...


-MCQ F45 Class:


1) how many types


2) this Types mediated by


3)Type of adaptive Immunity


4)Types Rapid or Delayed

Exaggerated (abnormal or Over)



TD Tissue damage



Failure of control



2ry



1)4


2)1st 3 > ABs, 4th > T cells


3)1st 3 > Humoral, 4th > CMI


4) 1st 3 > Rapid , 4th > Delayed

Ayman


MCQ Type I


Other names...


Mediated by which Ig...


Components

immediate



IgE



- Allergen


- IgE


- Cells


- Mediators

Allergen :


-presented to


-Ayman MCQ F45 Ex


-MCQ Important determinant


-MCQ IgE Mech


3)Cells


-Ayman Are


-MCQ IgE crosslink with w lead to...


4)MCQ F45 Mediators :


- Ayman Are


- eff on SM w ex...


-Ayman Mediators Lead to VC or VD w ⬆️ or ⬇️ Vascular Perm w lead to...


- eff on Mucus secretion...


-Eff on Nerve Endings w lead to...



- MCQ Precipitating Factors


TH2



Dust or food or drugs as Penicillin



Genetic predisposition



In Image



Mast w Eosinophils



Them ... Degranulation of them



HI Histamine w BK bradykinin w LK leukotrines.


هبل HBL



Contraction... bronchospasm



VD.... ⬆️Vascular Perm.... Hypovolemia w shock





➕ .... itching w pain



TH1⬇️ W ⬇️ IFN ¥ W Genetic

Ayman


Clincial Presentations

-Systemic (Generalized) : Anaphylactic shock


- Localized : Atopy

Ayman



1)Systemic


-MCQ Other name


-Characterized by


-MCQ result from Antigen Introduced by.


2)Localized


- MCQ Other Name


- Ex

Anaphylactic shock



Edema


⬇️BP


⬆️️Capillary Perm



Injection or Insect sting


حقنة او قرصة حشرة او Penicillin



Atopy




BA


Rhinitis


Urticaria

Ayman


Diagnosis


-List


Management :


-Anti shock Measures as w why


- Drugs as


- MCQ Allergen Immunotherapy as

-Allergic skin test (ID) : Wheal w flare


-Level of IgE



EP (VC) w CS .. Life saving



Mast cells stabilizers متفرقعش w Anti HI



Hyposensitization (Desensitization)

MCQ F45 Ayman


Desensitization :


- Doses مهمة فشخ


- Injected how


-To Stimulate Production of which Ig w this Ig prevent what

Gradually ⬆️



SC



IgG than IgE... Crosslinking (Blocking Ab)

MCQ


Type II :


-Ayman MCQ other name..


-Ayman MCQ Mediated by which Ig w against Antigen is w may be...


- Which of This Types part of CM w which is Attached to CM..


-Ayman At end Result is...


-Ayman MCQ Mech...


-Ayman Ex مهمة فشخ..

Cytotoxic



IgG or IgM... Cell + Antigen.. Endo or Exo (haptens)



Endo....Exo



Cell Lysis



ADCC


Phagocytosis (Opsonization)


Complement Activation



RIH


- Incompatible blood transfusion اشهر مثال


- Rheumatic Fever


- Penicillin and RBCs (Hapten) ➡️ hemolytic Anemia

MCQ


Type III :


-Ayman Other name


-Ayman Mediated by


-This Complex removed by (Again)


-MCQ This Type due to


-Depositing in Tissues a Damaging IR may develop through


-Ayman MCQ Ex

Immune-Complex (Ag-Ab complex)



IgG



MAC



Excess Production of Complex



- Complement Activation


- Attraction of polymorphs



- Serum thickness (Systemic)


- Arthus Reaction (Local)


- Glomerulonephritis


- Chronic Viral hepatitis


- AID autoimmune diseases

MCQ


Serum thickness :


-MCQ Causes : injection by w as in


-MCQ which Ig formed w What produced


-Ayman Theses deposited in w MCQ cause

IV... Plasma transfusion



IgG... Large amounts of soluble Immune Complex



Skin w Kidney w Joints.... Vasculitis w nephritis w arthritis.. Respectively

MCQ


Arthus Reaction :


-Ayman Local or systemic.


-Repeated?? Injections..


-Ayman Ex.

Local



SC



Insulin or penicillin or After rabies داء الكلب Vaccination

MCQ


Type IV...


-Ayman MCQ Other name...


-Ayman Sensitization of T cell by Ag how


-Ayman MCQ F45 Which type of adaptive


-Followed 1st or 2nd exposure w MCQ so Release


- MCQ what activate w ➕ or ➖ IR


-MCQ F45 Ex


-MCQ Which of Ex act as haptens w this ex as w this ex Characterized by

Delayed Type



Persistent Ag مش بيمشي



CMI



2nd... Lymphokines



MAC... ➕



- Tb Test (Mantoux) (local induration) ID skin test


- Contact dermatitis (eczema)



Contact Dermatitis.... Ni w cosemtics.. Mononuclear infiltration اللي هي ماك و تي سي