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12 Cards in this Set
- Front
- Back
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List 6 first generation Cephalosporins.
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1. cephalothin
2. cephapirin 3. cephadrine 4. cephalexin 5. cefazolin 6. cefadroxil |
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List 5 2nd generation cephalosporins.
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1. cefamandole
2. cefaclor 3. cefuroxime 4. cefoxitin 5. cefotetan |
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List 5 3rd generation cephalosporins.
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1. ceftriaxone
2. ceftazidime 3. cefotaxime 4. ceftizoxime 5. ceftibuten |
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List 1 4th generation cephalosporin.
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1. cefepime
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Ceftriaxone has the best CSF penetration and covers the bacteria that frequently cause meningitis. TRUE/FALSE
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TRUE. It is the first drug used in neonates for meningitis.
It is also used for gonorrhea. |
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What is Imipenem?
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It is a new class of beta lactam antibiotics called carbapenems.
It has the broadest antibacterial activity of any antibiotic known to man. |
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What bacteria are resistant to Imipenem?
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MRSA/some pseudomonas/ bacteria without peptidoglycan cell walls(Mycoplasma)
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The normal kidney has a dihydropeptidase that breaks imipenam down, so a selective enzyme inhibitor of this dihydropeptidase is given with imipenem. TRUE/FALSE
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TRUE. This inhibitor is called cilastin.
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Can Imipenem lower the seizure threshold?
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Yes.
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What is Meropenem?
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It is a newer carbapenem, as powerful as imipenem.
It is stable against dihydropeptidase, so cilastin is not needed. It does not as well lower the seizure threshold. |
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What is Aztreonam/
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It is a beta lactam antibiotic, but it is a monobactam(only has the beta lactam ring). It is considered by some to be a magic bullet for G- aerobic bacteria. it binds to the transpeptidase of Gram neg bacteria only.
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Aztreonam can kill Pseudomonas aeruginosa. TRUE/FALSE
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TRUE. It is often given with vancomycin and clindamycin.
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