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48 Cards in this Set

  • Front
  • Back

Red blood cells


(the cells on the left are crenated- RBCS in hypertonic solution)




•Normalvalue: 0–3 to 5/hpf


•Damageto glomerular membrane or vascular injury to the genitourinary tract•Numberof cells = extent of damage•Macroscopicversus microscopic hematuria–Cloudy, red urine, advanced disease,trauma, acute infection, coagulation disorders


–Clear urine, early glomerular disease,malignancy, strenuous exercise, renal calculi confirmation

Budding yeast

Glitter cells (WBCs in hypotonic solution)

WBCs in urine

Squamous epithelial cell- •Normalsloughing•Contaminationif not midstream clean-catch (vaginal/male urethra contamination)



What is a clue cell?

A clue cell is a squamous epithelial cells covered with the bacteria Gardnerella vaginalis.

Oval fat body (RTEs that have absorbed lipids)

What stain would you use to confirm the presence of hemosiderin in the urine sediment?

Prussian blue

What does Prussian blue stain?

Iron

What produces a maltese cross shape in polarized light?

Cholesterol (oval fat bodies)

Hyaline cast


0-2/lpf is normal

Why might hyaline casts be present in the urine?

Strenuous exercise, dehydration, heat exposure, emotional stress.

What type of protein is found in casts?

Tamm-horsfall protein (Uromodulin).

Waxy cast

Uric acid crystals; acidic pH

What disease is associated with uric acid crystals?

Gout

Uric acid crystals

Amorphous urates

Are amorphous urates found in acidic or alkaline urine?

Acidic.



You shake the cup of urine and observe pink foam. What does this signify?

Amorphous urates are present in acidic urine.

Calcium oxalate(acid/neutral)

What are calcium oxalate crystals associated with?

Renal calculi (kidney stones)

Calcium oxalate crystals can also be dumbbell and oval shaped

What are waxy casts associated with?

Chronic renal failure

Amorphous phosphates (alkaline urine)

Triple phosphate crystals (alkaline urine)



Triple phosphate crystals (alkaline urine)

Ammonium biurate (alkaline urine)

What type of crystal has a "thorny apple" appearance?

Ammonium biurate

Cystine Crystals (acidic urine)

Cholesterol crystals (acidic urine)

Leucine crystal (acidic urine)

Tyrosine crystals (acidic urine)

What type of crystals have a "shock of wheat" look?

Tyrosine crystals

Bilirubin crystals (acidic urine)

Leucine crystals (acidic urine)

These are not WBCs.  What are they?

These are not WBCs. What are they?

Renal tubular epithelial cells (RTEs)

Rod shaped bacteria in urine

You are observing urine sediment at low power. What magnification is this?

(10X power) so 100X magnification

You are observing urine sediment at high power. What magnification is this?

(40X power) so 400 x magnification.

What are "ghost cells"?

When RBCs are in dilute urine, they absorb water and lyse. The remaining, empty cell membranes are "ghost cells"

yeast (Mycelialforms)

yeast ( Mycelial forms)

RBCs identification difficulties

–Yeast: look for buds


–Oil droplets: refractility


–Air bubbles: refractility andpossibly in a different plane


Starch:refractile,polarizes

RBCs


Smooth,nonnucleated,biconcave disks ~7 µm

WBCs


Normal= <5 per hpf


granulated, multilobed neutrophils


mononuclear cells with abundant cytoplasm

clue cell - squamos epithelial cell covered in bacteria (Gardnerella vaginalis- vaginal infection)

Transitional Epithelial(Urothelial) Cells 1.Spherical: absorb water in bladder andbecome large and round


2.Caudate: appear to have a tail


3.Polyhedral: multiple sides