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30 Cards in this Set

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Neisseria (general properties)

Gram negative diplococci, oxidase positive, LOS, fastidious, chocolate agar and Thayer-Martin media, 5% CO2 for growth; non motile aerobic; cell wall antigens are lipooilgosaccharide

Neisseria gonorrhoeae

gonorrhoeae- pili, fimbriae, capsules, IgA protease


Men- inflammation in urethra, pus discharge


Women- asymtomatic, Pelvic inflam disease


Children- opthalmia neonatum (blind)

Meisseria Meningitidis

meningitis- 13 antigenic strain


causes blebbing- shedding outermembrane


college students and prisoners


septicemiapetechial hemorrhages on trunk and lower extremeties


shock, no vaccination against B strain

Enterobacteriaceae

Facultative anaerobes; oxidase negative; most common gram negative pathogens of humans. LPS, capsules, fimbriae, adhesins, exotoxins, siderpphores, hemolysins.

Enterobacteriaceae Coliform

Ferment lactose (growth on MacConkeys and emb) (e.coli, kelbsiella, serratia)

E. coli

coliform lactose fermenter


O,H,K antigens


O157:H7- severe bloody diarrhea


under cooked red meat


UTI; gastroenteritis

E. coli virotypes

ETEC: enterotoxigenic- travellers diarrhea


EPEC: enteropathogenic- traveller diarrhea


EHEC: enterohemorrhagic- bloody diarrhea


EIEC: enteroinvasive - bloody diarrhea

Klebsiella

coliform capsule inhibits phagocytosis; causes pneumonia with bloody sputum

Serratia

red pigment when grown at room temp. nosocomial - grows in catheters and salin solutions. oppertunistic

Proteus

enterobacteriacae non lactose fermentin non coliform. Swarming movement; urease positive, ammonia raises ph and ion precipitate; causes kidney stones. concentric rings of growth on plate

Salmonella

Non lactose fermenting true pathogen of enterobacteriacae, syringe needle system urease and oxidase positive; produces H2S; contaminated poultry and eggs; Salmonelosis- diarrhea; Typhoid fever- serotype typhi, peritonitis

Shigella

non lactose fermenting true pathogen of enterobacteriae. shigellosis- abdominal cramps, diarrhea, bloody stools.


Four well defined species : S. dysenteriae - makes shiga toxin that acts on 60S ribosome and stops protein synthesis, S. flexneri, Sboydii,Ssonni.

Yersinia

non lactose fermenting true pathogen of enterobacteriae.


Y. enterocolitica- diarrhea, painful inflammation of lymph nodes.


Y. Pseudotuberculosis- less severe than enterocolitica


Y. Pestis- bubonic plague; pneumonic plague-airborne transmission; swelling lymph nodes (buboes); mice are

Pasteurella

gram negative facultative anaerobe bacilli pasteurellaceae. Normal microbiota of animals. humans infected via bites or aerosols. Localized inflammation and lymph node swelling occurs. Cultured on blood/choco agar

Hemophilus influenzae

gram negative facultative anaerobe bacilli (plemorphic) pasteurellaceae. require heme and NAD+ for growth- obligate parasite.


-influenzae: has polysaccharide capsule that resists phagocytosis. type b- causes meningitis in young children before Hib vaccine causes swellin of the epiglottis

Hemophilus ducreyi

gram negative facultative anaerobe bacilli pasteurellaceae. require heme and NAD+ for growth- obligate parasite. STD causes painful, soft, genital ulcer (chancroid/ soft chancre.

Bartonella Bacilliiformus

gram- aerobic bacilli. fastidious 37 with CO2


invades and weakens erythrocytes


bartonellosis- fatal fever anemia and muscle pain


Sand flies (phlebotomus) transmit this

Bartonella Quintana

gram- aerobe


trench fever- 5 day recurring fever


body lice transmission


headaches, fever, pain in the long bones

Bartonella Henselae

gram - aerobe bacilli


Cat-scratch disease- fleas and scratches in children


Prolonged fever, localized swelling and swelled lymph nodes


Angiogenisis- formation of new vessels

Brucella

Gram- aerobic bacilli


zoonotic disease


causes abortions or sterility


brucellosis


undulant fever

Bordetella Pertusis

Whooping cough- destroy ciliated epithelial cells of trachea


Incubation - no symptoms


catarrhal- common cold like symptoms


paroxysmal- whoops


convalescent - cilia grow back


DTaP; bordet-gengou medium

Bordetella Pertusis Adhesins and Toxins

Adhesins- Hemagglutinin, pertusis toxin


Toxins


Pertusis toxin- increased mucus production


adenylate cyclase toxin- increases mucus


dermonecrotic toxin- localized consrtiction and hemorrhage of blood vessels, tissue destruction


tracheal cytotoxin- destroys cilia

Burkholderia cepacia

can decompose a broad range of organic molecules - is an oppertunistic pathogen of cystic fibrosis patients


Used for clean up

Burkholderia pseudomallei

meliodosis- bioterror agent in tropics of southeast asia and australia

Pseudomonas aeruginosa

can survive in disinfectants/ contact solution


Oppertunistic


pyocyanin- blue-green pigment


burn victims and cystic fibrosis


Moraxella catarrhalis- sinus bronchi ears


Acinobacter- res,urinary, CNS

Francisella tularensis

Rabbit fever


swollen lymph nodes


tick fleas, mosquito bits


tularemia


bioterror agent

Legionella

legionnaires' disease


l pneumophila


moist environments AC ducts, shower, spa


Charcoal yeast extract agar

Coxiella

Q fever


small obligate intracellular parasite


ineffective body- used for survival


Infects wide range of mammalian and avian hosts


ticks


rancher and vets are most susceptible


20 day incubation period, mild pneumonia high fever and chills

Bacteroides

anerobic bacillus


causes gastroenertitis (GIT 85%)


grows wells on bile eschulin plate, black colonies


enterococcus similar clinically


Metronazidole is the drug of choice


lipid a is not as toxic

Prevotella

anerobic bacillus bile sensitive


does not grown in intestinal tract


sinus and ear infections


brain abcesses