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30 Cards in this Set
- Front
- Back
Neisseria (general properties) |
Gram negative diplococci, oxidase positive, LOS, fastidious, chocolate agar and Thayer-Martin media, 5% CO2 for growth; non motile aerobic; cell wall antigens are lipooilgosaccharide |
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Neisseria gonorrhoeae |
gonorrhoeae- pili, fimbriae, capsules, IgA protease Men- inflammation in urethra, pus discharge Women- asymtomatic, Pelvic inflam disease Children- opthalmia neonatum (blind) |
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Meisseria Meningitidis |
meningitis- 13 antigenic strain causes blebbing- shedding outermembrane college students and prisoners septicemiapetechial hemorrhages on trunk and lower extremeties shock, no vaccination against B strain |
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Enterobacteriaceae |
Facultative anaerobes; oxidase negative; most common gram negative pathogens of humans. LPS, capsules, fimbriae, adhesins, exotoxins, siderpphores, hemolysins. |
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Enterobacteriaceae Coliform |
Ferment lactose (growth on MacConkeys and emb) (e.coli, kelbsiella, serratia) |
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E. coli |
coliform lactose fermenter O,H,K antigens O157:H7- severe bloody diarrhea under cooked red meat UTI; gastroenteritis |
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E. coli virotypes |
ETEC: enterotoxigenic- travellers diarrhea EPEC: enteropathogenic- traveller diarrhea EHEC: enterohemorrhagic- bloody diarrhea EIEC: enteroinvasive - bloody diarrhea |
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Klebsiella |
coliform capsule inhibits phagocytosis; causes pneumonia with bloody sputum |
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Serratia |
red pigment when grown at room temp. nosocomial - grows in catheters and salin solutions. oppertunistic |
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Proteus |
enterobacteriacae non lactose fermentin non coliform. Swarming movement; urease positive, ammonia raises ph and ion precipitate; causes kidney stones. concentric rings of growth on plate |
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Salmonella |
Non lactose fermenting true pathogen of enterobacteriacae, syringe needle system urease and oxidase positive; produces H2S; contaminated poultry and eggs; Salmonelosis- diarrhea; Typhoid fever- serotype typhi, peritonitis |
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Shigella |
non lactose fermenting true pathogen of enterobacteriae. shigellosis- abdominal cramps, diarrhea, bloody stools. Four well defined species : S. dysenteriae - makes shiga toxin that acts on 60S ribosome and stops protein synthesis, S. flexneri, Sboydii,Ssonni. |
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Yersinia |
non lactose fermenting true pathogen of enterobacteriae. Y. enterocolitica- diarrhea, painful inflammation of lymph nodes. Y. Pseudotuberculosis- less severe than enterocolitica Y. Pestis- bubonic plague; pneumonic plague-airborne transmission; swelling lymph nodes (buboes); mice are |
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Pasteurella |
gram negative facultative anaerobe bacilli pasteurellaceae. Normal microbiota of animals. humans infected via bites or aerosols. Localized inflammation and lymph node swelling occurs. Cultured on blood/choco agar |
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Hemophilus influenzae |
gram negative facultative anaerobe bacilli (plemorphic) pasteurellaceae. require heme and NAD+ for growth- obligate parasite. -influenzae: has polysaccharide capsule that resists phagocytosis. type b- causes meningitis in young children before Hib vaccine causes swellin of the epiglottis |
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Hemophilus ducreyi |
gram negative facultative anaerobe bacilli pasteurellaceae. require heme and NAD+ for growth- obligate parasite. STD causes painful, soft, genital ulcer (chancroid/ soft chancre. |
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Bartonella Bacilliiformus |
gram- aerobic bacilli. fastidious 37 with CO2 invades and weakens erythrocytes bartonellosis- fatal fever anemia and muscle pain Sand flies (phlebotomus) transmit this |
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Bartonella Quintana |
gram- aerobe trench fever- 5 day recurring fever body lice transmission headaches, fever, pain in the long bones |
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Bartonella Henselae |
gram - aerobe bacilli Cat-scratch disease- fleas and scratches in children Prolonged fever, localized swelling and swelled lymph nodes Angiogenisis- formation of new vessels |
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Brucella |
Gram- aerobic bacilli zoonotic disease causes abortions or sterility brucellosis undulant fever |
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Bordetella Pertusis |
Whooping cough- destroy ciliated epithelial cells of trachea Incubation - no symptoms catarrhal- common cold like symptoms paroxysmal- whoops convalescent - cilia grow back DTaP; bordet-gengou medium |
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Bordetella Pertusis Adhesins and Toxins |
Adhesins- Hemagglutinin, pertusis toxin Toxins Pertusis toxin- increased mucus production adenylate cyclase toxin- increases mucus dermonecrotic toxin- localized consrtiction and hemorrhage of blood vessels, tissue destruction tracheal cytotoxin- destroys cilia |
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Burkholderia cepacia |
can decompose a broad range of organic molecules - is an oppertunistic pathogen of cystic fibrosis patients Used for clean up |
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Burkholderia pseudomallei |
meliodosis- bioterror agent in tropics of southeast asia and australia |
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Pseudomonas aeruginosa |
can survive in disinfectants/ contact solution Oppertunistic pyocyanin- blue-green pigment burn victims and cystic fibrosis Moraxella catarrhalis- sinus bronchi ears Acinobacter- res,urinary, CNS |
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Francisella tularensis |
Rabbit fever swollen lymph nodes tick fleas, mosquito bits tularemia bioterror agent |
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Legionella |
legionnaires' disease l pneumophila moist environments AC ducts, shower, spa Charcoal yeast extract agar |
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Coxiella |
Q fever small obligate intracellular parasite ineffective body- used for survival Infects wide range of mammalian and avian hosts ticks rancher and vets are most susceptible 20 day incubation period, mild pneumonia high fever and chills |
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Bacteroides |
anerobic bacillus causes gastroenertitis (GIT 85%) grows wells on bile eschulin plate, black colonies enterococcus similar clinically Metronazidole is the drug of choice lipid a is not as toxic |
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Prevotella |
anerobic bacillus bile sensitive does not grown in intestinal tract sinus and ear infections brain abcesses |