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16 Cards in this Set
- Front
- Back
Peptidoglycan monomer
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NAM and NAG molecules bonded to a tetrapeptide
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What is the function of peptidoglycan?
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Gives bacteria shape and prevents osmotic lysis
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Autolysins
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bacterial enzymes break cross links between peptidoglycan monomers during growth of cell wall
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Transpeptidase
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enzymes that add new peptidoglycan monomers and reseal cell wall during cell growth
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How do penicillins interfere with cell wall growth to kill bacteria?
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They bind to transpeptidase enzymes so they cannot cross-link peptidoglycan monomers
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How do cephalosporins interfere with cell wall growth to kill bacteria?
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They bind to transpeptidase enzymes so they cannot cross-link peptidoglycan monomers
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How do glycopeptides interfere with cell wall growth to kill
bacteria? |
They bind directly to peptides in the cell wall and block then from cross-linking
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What color are gram-positive bacteria when stained and why?
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Purple, because they retain the initial dye crystal violet
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What color are gram-negative bacteria when stained and why?
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Pink, because they pick up the counterstain safranin
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What color are acid-fast bacteria when stained and why?
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Red, because they retain the initial dye carbolfuchsin
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teichoic acids
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acids found in the cell wall of gram-positive bacteria
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pathogen-associated molecular patterns
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molecules unique to microorganisms that the body detects as being foreign.
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What percent of the cell wall of a gram-positive bacteria is peptidoglycan?
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60-90%
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How thick is the gram-positive cell wall?
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20-80 nm
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How thick is the gram-negative cell wall?
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2-3 nm
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What percent of the cell wall of a gram-negative bacteria is peptidoglycan?
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10-20%
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