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10 Cards in this Set

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  • Back

What are some of the skin's defenses from harmful microorganisms?

1. Keratinized cells on outermost layer of epidermis.


2. Constant sloughing off of dead skin cells from the stratum corner


3. Sebum, secreted fromt he sebaceous gland- low pH, toxic to some microorganisms


4. Sweat, also low pH, high salt, and lysozyme


5. Antimicrobial peptides in epithelial cells

Sweat is one of the skin's defenses against harmful microorganisms because it contains lysozyme. What is Lysozyme?

Lysozyme is an enzyme that breaks down peptidoglycan. Peptidoglycan is a component in bacterial cell walls.

What are the 3 main microorganisms on the skin's normal biota?

Diptheroids, micrococci, and yeasts.


Three main categories of microorganisms reside on the skin. This includes all of the following EXCEPT

A) diphtheroids.


B) micrococci.


C) yeasts.


D) enterics.

D) Enterics

One of the chief reasons that the microbial count on skin is relatively low is due to ___________ found in epithelial cells, which work by disrupting bacterial membranes.

A) antimicrobial peptides


B) low pH


C) high salt content


D) lysozymes

A) Antimicrobial peptides

This organism lives on 20-30% of humans, but is so capable of causing serious disease it is considered "abnormal biota." It can grow in a wide temperature range and is able to metabolize many compounds as nutrients.
Staphylococcus aureus

How does acne form on skin?

overproduction of sebum caused by hormones. Sebum is trapped in hair follicle along with dead skin cells.


Propionibacterium acnes in the follicle releases lipases to digest extra oil. Combination of the metabolites and bacterial antigen causes intense local inflammation that can eventually burst the follicle. Is anaerobic or aerotolerant

True or False:


Acne is a hair follicle lesion

True



What are the types of lesions in acne?

Comedo- your standard zit. Closed pore is a white head, open but blocked with a sebum plug is a blackhead.


pustule/papule- when the lesion erupts on the surface


cyst- pustules that involve deeper layers of skin