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14 Cards in this Set

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A 30 year old IV drug abuser is at risk for what infection?
What will be damaged as aresult?
IV drugs allow Staph aureus to enter- can cause endocaditis damage to the valves
A woman presents to the ER with 6 presentations of TSS
What are they?
1. Erythrematous rash
2. Vommiting
3. Hypotension
4. Fever
5. Diahhrea
6. Desquamating palms/soles
What 9 conditions can Staph cause?
1. Bacteremia
2. UTI
3. Meningitis
4. Pneumonia
5. Septic Arthritis
6. Osteomyelitis
7. Sepsis
8. Skin infection
9. Acute endocarditis
BUMP SOSSA
How do Staph evade the immune system
Protein A - prevents phagocytosis
Leukocidines- Destroy WBC
Staph A has coagulase helps conceal bacteria from Immune System
HOK antigens are associated with ehat bacteria
E-Coli
Which bacteria is constantly changing its antigen to avoid detection?
Shigella is constantly changing its H antigen to avoid detection
The H antigen in Shigella allows it ti avoid detection
T/F?
False, shigellla has NO flagella therefore no H antigen.
Salmonella has an H antigen
All E Coli are pathogenic
T/F?
False, it is part of the normal flora. It is the plasmid or TRANSPOSON insertion that makes it pathogenic
Case: A 5 yr old ate a hamburger and developed renal failure with thrombocytopne and anemia
What could be the cause?
Enterohemorrhagic E Coli
Primarily in cattle: beef and unpasteurized milk. It can cause Hemolytic Uremic Syndrome (HUS) in children <10 as well as diarrhea (shigella like toxin)
50 year old woman visits Italy where she developes diarrhea,
What could be the cause- include molecular mechanism?
ETEC- enterotoxic e-coli
HST and HLT are responsible
No NaCl reabsorption
Cl and HCO3 excreted carring all the water with it
Which toxin binds the 60s ribosome preventing protein synthesis
What does this cause?
EHEC- Shigella like toxin prevent protein synthesis Epithelium cant repair and causes bleeding in stool
What diseases are caused by E Coli?
Diarrhea, Neonatal meningitis, UTI and Sepsis
DUNS
Enterotoxin causes sepsis in E Coli
T/F?
Flase, Lipid A which is an endotoxin leads to sepsis
Which of the following are true
Salmonella
1. Ferments lactose
2. Ferments glucose
3. Does not produce H2S
4. Has a K antigen
5. non-motile
Salmonella
+ H2S
+ Lactose
- Glucose
- K antigen (has Vi)
+ Motile