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14 Cards in this Set

  • Front
  • Back

Gram positive cocci

Staphylococcus aureus


Staphylococcus epidermis


Strep pyogenes


Strep agalactiae


Strep viridans


Strep pneumonia


Organism:


Staphylococcus aureus


(Disease and Introduction)

Disease: multiple


Introduction: Gram positive cocci arranged in grape-like or irregular clusters. Gold colored colonies.


- asymptomatically in 20-40% adults


-50-70% nosocomial


-Produce coagulase (+): which enhances its virulence.


- Thermophile: heat resistant for 60* for 30 minutes. Resistant to desiccation.

Staphylococcus aureus


(Pathogenicity)

TSS: toxic shock syndrome:


- tampons


- Exotoxins


- Fever, rash, desquamation


Gastroenteritis:


- food poisoning toxemia


- Enterotoxin


- Starchy food


- Heat stable


Scalded skin syndrome:


- Diffusible exotoxin


- Infants and children under the age 5


Skin infections


Folliculitis, furuncles, carbuncles


- Impetigo: epidermal infection causing crust, scabs and fever


Wound infections: most common nosocomial


Osteomyelitis:


Rare bone infection


Enteritis


Pneumonia


Infective endocarditis


Pyogenic arthritis



Staphylococcus Aureus


(Diagnosis, treatment, prevention)

Dx:


- coagulase test


- Ferments mannitol when grown on Mannitol salt agar


- the high salt content inhibits all growth but staphylococcus.


Rx:


Antibiotics


Prevention:


Hygiene for wounds


Refrigeration of starchy foods

MRSA

Methicillin resistant Staphylococcus aureus


- Resistant to methicillin


RX: Vancomycin

Staphylococcus epidermis


(Disease and introduction)

Disease: opportunistic


Intro: Gram positive cocci


Normal skin flora


Grows white colonies

Staphylococcus epidermis


(Pathogenicity)

- Opportunistic


Biofilms, IV Caths, eye infections, plaque, prosthetics

Staphylococcus epidermis


(Management and control)

- Non chromogenic


- Does not ferment on mannitol agar.


- Does not produce coagulase


Rx: antibiotics


Pyogenic Streptococci

- Gram + cocci occulting in chains


- put in groups based on C carbohydrate: Lancefield groups. (A-H and K-U)


- Cell wall M protein: anti-phagocytic important in virulence.

Two types of Lancefield groups?

(A-H & K-U)


Group A: human pathogens


Group b: cattle and humans

Extracellular products produced by streptococci

Hylauronidase: (Spreading factor) by digesting hyaluronic acid.


Streptokinase: produces but group A. Digests clots allowing bacteria to escape.


Pyrogenic exotoxins: Stimulates leukocytes to releases cytokines.


Hemolysins:


Lyse membranes damages other cells. 1. Streptolysin O 2. Streptolysin S



Organism: Streptococcus pyogenes, group A Strep


(Diseases and intro)

Gggg

Corynebacterium diphtheria


(Disease and introduction)

- Gram positive non spore forming aerobic acid. Club shaped appearance.


- Irregularly distributed within the rods are metachromatic granules. (Stain red with blue dye)


- Tend to lie parallel or acute angles to each other.


- Spread by droplet (respiratory) or direct contact with wounds.

Corynebacterium diphtheria


(Pathogenicity)

- Respiratory diphtheria


- Diphtheria toxin absorbed into mucous membranes and cause destruction of epithelium


- Necrotic epithelium becomes grayish pseudomembrane.


- affects organs and nerve damage.


- Begins with low grade fever followed by prostration and dyspnea.


Cutaneous diphtheria- chiefly occurs in the tropics.