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14 Cards in this Set

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  • Back
What's the main characteristic of mycoplasma/ureaplasma species?
They lack a peptidoglycan cell wall. Gram stain results in NO SIGNAL.
What unusual component is found in mycoplasma/ureaplasma cell membranes?
Cholesterol
Where do mycoplasma/ureaplasma derive most of their nutrition?
From their host.
What are the four primary species of Mycoplasma/Ureaplasma associated with human disease?
1. M. pneumoniae
2. M. hominis
3. M. genitalium
4. U. urealyticum
What's one of the most common lung infections?
M. pneumoniae pneumonia, 10% of all cases.
Who's at risk for M. pneumoniae PNM?
Ages 5-20, but everyone is susceptible.
What's the pathogenesis of M. pneumoniae URI?
Attaches to cilia/microvilli/bronchial epithelium via P1 Protein, a cyto-adhesin
What circulatory disease is associated with auto-immunity from M. pneumoniae infection?
Raynaud's, from IgM/cold haemagglutinin response
What are the clinical manifestations of M. pneumoniae PNM?
Atypical ("Walking") Pneumonia
* Long incubation
* Minimal cough
* Mild disease, self-limiting
What derm disease is associated with auto-immunity from M. pneumoniae infection?
Stevens-Johnson Syndrome
What antibiotics are used to treat M. pneumoniae PNM?
Macrolides (erythro, azythro) or Quinolones
What mycoplasma is an STD?
Mycoplasma gentalium
What symptoms are associated with M. genitalium infection in men and women?
Urethritis in men, mucopurulent cervicitis in women.
How are M. genitalium and U. urealyticum diagnosed?
Serodiagnosis