Micro Chapter 21 And Chapter 22 True/false Review

Front 1

True or False? The antigenic determinant site is a geographical location on the antigen molecule that often consists of a number of molecules.

Back 1

True

Front 2

True or False? The immune system will attack "self" only under conditions of enhanced specific immunologic tolerance

Back 2

False; the immune system will attack "self" only if self-tolerance breaks down

Front 3

True or False? Antibody response to a hapten occurs before the hapten has combined with tissue proteins or polysaccharides to form a complete antigen.

Back 3

False; Haptens have to combine with tissue proteins or polysaccharides first

Front 4

True or False? Immunogens are antigens

Back 4

True

Front 5

True or False? Most immunogenic molecules are large, complex that are not normally present in the body

Back 5

True

Front 6

True or False? In an immune response, it is important that the response be strong enough to eliminate the pathogen yet controlled so as not to cause extensive damage to the tissues and organs of the body

Back 6

True

Front 7

True or False? On antigenic stimulation, the plasma cells revert to B lymphocytes, which produce antibodies for humoral immunity

Back 7

False; it's the other way around: on antigenic stimulation, B lymphocytes transform to plasma cells producing antibodies for humoral immunity

Front 8

True or False? The genetic code for synthesizing the surface receptor is present in an individual even though the individual has not ever been exposed to that antigen

Back 8

True

Front 9

True or False? Innate immunity is due to the specific production of T cell and B cell clones in response to an antigen

Back 9

False; Acquired immunity is specific while innate immunity is nonspecific

Front 10

True or False? A large percentage of developing T and B cells that normally would react with self antigens, are destroyed respectively in the thymus and bone marrow through apoptosis

Back 10

True

Front 11

True or False? The Fc and Fab fragments refer to sites on the antigen molecule that stimulate antibody production

Back 11

True

Front 12

True or False? The secretory antibody IgA may be found in the tears, saliva, gastrointestinal tract and colostrum

Back 12

True

Front 13

True or False? During a secondary immune response, B cells are activated and the effector cells and the plasma cells, start producing and secreting antibody. There is a lag of several days before any measurable antibodies appear

Back 13

False; this is a description of the primary response

Front 14

True or False? The mixing and matching of immunoglobulin gene segments produces unique antibodies

Back 14

True

Front 15

True or False? The process of somatic recombination is a random mixing and matching of antibodies to form unique antigen molecules

Back 15

True

Front 16

True or False? Activated T cells help with both cellular and humoral immunity

Back 16

False; Activated T cells help with cellular immunity only

Front 17

True or False? I MHC proteins are found on all nucleated cells of the body. If these proteins contain an antigen fragment from an infecting virus, cytotoxic T cells will bind to it with their TCR/CD8 receptor complex

Back 17

True

Front 18

True or False? In the preparation of toxoids, the antigenicity of the toxin remains while the toxigenicity is destroyed

Back 18

True

Front 19

True or False? A danger of subunit vaccines is that disease may occur in immuno-incompetent person who is vaccinated

Back 19

False; subunit vaccines cannot produce disease in the person vaccinated

Front 20

True or False? Naturally acquired active immunity to a particular disease may occur when antibodies cross the placenta from the mothers circulation to that of the fetus

Back 20

True

Front 21

True or False? Immunizing agents include toxoids, subunit vaccines containing parts of microorganisms, and recombinant vaccines such as that used for hepatitis B

Back 21

True

Front 22

True or False? The phenomenon of herd immunity says when approximately 90 percent of the population is vaccinated, the spread of the disease is effectively stopped

Back 22

True

Front 23

True or False? The titer of antibody is the most concentrated amount of serum that yields a detectable reaction with its specific antigen

Back 23

False; the titor of antibody is the most diluted

Front 24

True or False? Immunoelectrophoresis techniques are based in part on the precipitation reaction that takes place between antigens and antibodies

Back 24

True

Front 25

True or False? In precipitation reactions, antigens on the surfaces of particles react with antibodies and cause the cells to precipitate to the bottom of the vessel

Back 25

True

Front 26

True or False? The indicator system in the complement fixation test is used to determine whether complement was used up in the test system

Back 26

True

Front 27

True or False? Antiglobulin antibodies are those that interact with human antibodies such as in fluorescent antibody techniques

Back 27

True

Front 28

True or False? The direct fluorescent antibody test requires that antiglobulin antibodies be used, while the indirect test has no such requirement

Back 28

False; the direct fluorescent antibody test doesn't require that antiglobulin antibodies be used while the indirect test requires that antiglobulin antibodies be used

Front 29

True or False? The radioallergosorbent test (RAST) can be used to detect IgE antibodies in the serum of a person possibly allergic to penicillin

Back 29

True

Front 30

True or False? The ELISA test has virtually the same sensitivity as RIA and RAST but does not require expensive equipment or radioactivity

Back 30

True

Front 31

True or False? Monoclonal antibodies are produced by carcinoma cells

Back 31

False; Monoclonal antibodies are produced by myeloma cells

Front 32

True or False? The Fc fragment can combine with phagocytes in opsonization; it may activate the complement system in resistance mechanisms; or it might attach to certain cells in allergic reactions

Back 32

True