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21 Cards in this Set
- Front
- Back
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A 1st line of diffence |
1st Innate body defenses Mucus and Intact skin 2nd phagocytic defence 3rd Antibody defense 3rd |
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Intact skin |
Physical and chem barrier |
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Mucus membranes |
Hair Ciliated cells Tear saliva and mucus |
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Normal flora and biota |
Barrier and Bacteriocin production |
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Blood brain barrior |
Ssmsmks Ependymal cell And astrocytes •Microglial cells (phagocytes) in the region |
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Oxygen tension |
Aerobic (lungs) Anaerobic (intesines) |
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Iron levels Non agro deffence |
Microbes require Fe++ During infection -->hypoferemia |
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Defication vomiting |
Ridding microbes |
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Fever |
Release of pyrogens |
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Benifits of low grade fever |
Incr in immune mechanism Incr in phagocytes Incr in onterferon Inhibits growth of certain microbes |
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Aggressive types of defence |
A |
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Lysozyme |
Gram pos bacteria Found in tears saliva Perspiration and granules of neutrophils |
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Sebum |
Fatty acids toxic to gram neg |
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Cydal agents |
Shhs |
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Compliment |
Gram neg And Viruses Serum proteins Exists in an inactive state Consists of 30+ proteins When active: low grade fever Once activated it attaches to the microbe and destroys it
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Cydal agent interferon |
Antiviral protein All cells produce this in small amounts Protects uninfected cells from being infected by the virus Given in large doses for various therapeutic reasons Djndnem |
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Leukins |
Cydal agent produced by leukocytes WBC
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Plakins |
Cydal agent produced by platelets |
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Lactoferrin Transferrin Pg 4 |
Breast milk tears and neutrophils Serum protein Regulates the absorption transportand metabolism of Fe++ |
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Phagocytosis |
Cells capable of ingesting Microbes debris or foriegn matter |
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Steps of phagocytosis |
1 chemotaxis 2 adherance (capsole can prevent Oposonization( opsonin proteins 3 ingestion (phagocytic vacuole or phagosome) waxy cell wall can prevent 4 digestions (lysosomes) 5 release or discharge |
