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9 Cards in this Set
- Front
- Back
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Autoimmunity mean... |
Breakdown in Recognition and Immune System Destroys its own Tissues |
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Etiology يعني ايه |
اسباب |
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Etiology |
1. Microbial antigens 2. Superantigen 3. Altered self-Antigen 4. Trauma 5. Defect in deletion of self Reactive Lymphocytes during development and Maturation 6. ⬇️T Regulatory |
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Microbial antigens... With self-components. .. Superantigen... Induce.. Altered self-Antigen... Occ under effect of... Ex.. Trauma... Lead to.. Ex.. Defect in deletion of??? During development and Maturation |
Cross-react
Polyclonal stimulation.
Drugs... Penicillin
Exposure of self-Antigens... Brain w cornea w lens of eye
Self Reactive Lymphocytes |
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Mech of TD Tissue damage |
-AB mediated (Type 2 w 3 hypersensitivity) -Cell-Mediated (Type 4 hypersensitivity) -Mixed |
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Ex |
Behcet's disease Sjogren Syndrome SLE Systemic lupus erythematosis |
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Behcet's disease... Cause : inflammation in.. Signs and symptoms |
BV
-Mouth w genital sores - Eye inflammation - Skin rashes |
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Sjogren... Cause : injuries of w Signs and symptoms |
moisture-producing glands
-Dryness in mouth w eyes - other parts of body can be affected |
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SLE.... Which AB formed w Signs and symptoms : what organ can affected w where ulcer May happened .. Type of disease |
ANA antinuclear
many diff body systems ... Mouth and nose
Immune Complex mediated |
