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19 Cards in this Set

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Migrane abortive therapy

  1. NSAIDS + prokinetic
  2. Triptans (5HT 1b/1d agonist)

  • sumatiptan, rizatriptan,



should not use >10 days/ month

migrane preventive tx

>2 attacks per month





  1. beta blockers - propanalol
  2. TCA - amitryptaline
  3. CCB - flunarizine
  4. 5HT agonist - Pizotifen
  5. AED - topiramate, valproate

cluster headache mx

abortive



  1. 100% O2 6 l/min for 6 min
  2. sumatriptan SC or IM
  3. short course of steroid



Preventive



  1. verapamil
  2. lithium
  3. topiramate / valproate

Anterior spinal artery syndrome

supply ant 2/3 of spinal artery



  • radicular pain at onset
  • sudden para/quadraplagia
  • flaccid limbs changes to spastic limbs over days
  • areflexia becomes hyperreflaxia over days
  • pain, temp, touch pressure loss of sensation
  • urinary retension
  • preserved vibration and proprioception

tabes dorsalis


  • posterior spinal root and poserior dorsal colum dysfunction
  • syphilis
  • pupillary abnormalitis (argyll robertson)
  • areflexia
  • joint poition and vibration loss
  • sensory ataxia
  • can develop charcot joint - due to loss of sensation
  • urinary incontinance, impotence, constipation




Sub acute combined degenaration of the spinal cord

b12 deficiency causes



  • diet
  • increased need - pregnancy
  • defective absrption - pernicious anaemia / gastic sx/ malasoptive syndromes (pancreatitis, tape worm)



spinal cord demylination + later axonal injury


lower cord - post column and lateral column


upper cord - posterior column




Tx


initial tx- 1000 micrograms IM for 3-7 days


then weekly for 4 weeks


maintance for life time





subacute combined degeneration of the spinal cord - clinical features

clinical features



  1. sub acute onset
  2. parastheis of extremities
  3. numbness, vibration n joint position loss
  4. glove n stokin sensory loss
  5. distal wasting
  6. motor power reduced distally
  7. extensor planter reflex
  8. unstady and spastic walk
  9. rombergs positive - sensory ataxia
  10. optic atropy
  11. cerebral demylination
  12. dementia

Bone disease in ckd

  1. Osteitis fibrosa cystica- bone turnover is increased due to secondary hyperparathyroidism
  2. Adynamic bone disease - bone turnover is low. most current cases result from excessive suppression of the parathyroid gland
  3. Osteomalacia - bone turnover is also low in combination with an increased volume of unmineralized bone
  4. Mixed uremic osteodystrophy

Commence antivenom therapyimmediately for the bites of

  1. Russles
  2. cobra
  3. krait (both)
  4. saw scale

do not give antivenom for

hump node


green pit


sea snake

when to give antivenom

its never too late to give antivenom given that there is




systemic envenoming


except in cobra -if half the limb is involved





Heart failure Killip classification

Killip I - no crackles, no S3


Killip II - crackles in <50% of lung feilds OR S3


Killip III - crackels in >50% of lung feild


Killip IV - cardiogenic shock

common nurological signs in wilsons

early presentation



  • difficulty speaking,
  • excessive salivation,
  • ataxia,
  • masklike facies,
  • clumsiness with the hands,
  • personality changes



late



  • dystonia,
  • spasticity,
  • grand mal seizures,
  • rigidity,
  • flexion contractures

caplan syndrome

rheumatid arthritis and pneumoconiosis




auscultation - rattling sound


cxr - well defined round nodules

causes for reverse splitting

electrial delay


- LBBB


anything that causes delayed clouser of A2


- systolic hypertension


- AS


- left ventricular failure


anything that fills pulmonary system sooner


- PDA

wide spliting of S2

Early A2



  • MR
  • VSD



delayed P2



  • RBBB
  • PS
  • ASD
  • RVF

paroxysmal Nocturnal Hemoglobinuria - features

haemolytic anaemia


thrombophilia and thrombosis in large vessals


aplastic anaemia / pancytopenia

pericarditis ECG


  • Widespread concave ST elevation (sandle shape) and PR depression throughout most of the limb leads (I, II, III, aVL, aVF) and precordial leads (V2-6).
  • Reciprocal ST depression and PR elevation in lead aVR (± V1).
  • Sinus tachycardia is also common in acute pericarditis due to pain and/or pericardial effusion.

Social history

* A- adl
* B - boarding place
* C - caregivers
* D - depression
* E - education
* F - finance
* G - gay / sexual activities
* H - nearest hospital and transportation / habbits
* I - insight