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30 Cards in this Set
- Front
- Back
the study of how medications enter the body reach their site of action, metabolize and exit the body
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PHARMACOKINETICS
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the effects of the medications combined is greater than the effect of the medication when given seperately.
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Synergistic effect
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expected or predictable response a medication causes
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Therapeutic effect
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unintended, secondary effects a medication predictably will cause
-harmless, injurious |
Side effect
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severe responses to medications
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Adverse effect
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excessive amounts of meds within the body may have lethal effects
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Toxic effect
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unpredictable effects a client overreacts or underreacts to a medicatio, or has a reaction different from normal.
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Idiosyncratic reaction
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unpredictable response
makes up 5 to 10% of all meds reactions client becomes sensitized immunologically to a dose |
allergic reaction
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sudden constriction of bronchiolar muscles, edema of pharynx, wheezing, SOB
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Anaphylactic Shock
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Name factors that influence medication absorption?/
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route of administration
ability of meds to dissolve blood flow to site of admini body surface area lipid solubility of medicatio food in stomach |
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time of absorption?
Skin? Mucous membranes? Oral? IV injection? |
Skin= slow
mucous membrances= quick oral= slow IV,injection= MOST RAPID |
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time of absorption?
oral meds? solutions/preparation? acidic meds? basic meds? |
oral meds=depends on preparation
sol/prep= liquid(quicker) acidic=RAPID (STOMACH) basic=absorb in sm.intestine |
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Blood Flow absorption?
Body surface area? Lipid solubility? |
rich blood supply=fast absorption time
larger surface area=faster rate of absorption high lipid solubility=easy absorption |
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all medication orders to include?
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-date
-time -pt name -drug name -dosage(amount,frequency) -route -signature |
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The highest serum concentration of the medication usually occurs just before the last of the medication is absorbed
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PEAK CONCENTRATION
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MINIMUM BLOOD SERUM CONCENTRATION OF MEDICATION REACHED JUST BEFORE THE NEXT SCHEDULE DOSE?
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TROUGH CONCENTRATION
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when is the trough level drawn?
when is the peak level drawn? |
trough: 30 minutes before the drug is administered
peak: whenever the the drug is expected to reach its peak concentration |
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the time it takes for excretion processes to lower the serum medication concentration by half?
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SERUM HALF LIFE
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given via epidural space via a catheter,
most commonly used for the administration of analgesia? |
Epidural
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given through a catheter placed into the subarachnoid space or into one of the ventricles of the brain?
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Intrathecal
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involves the infusion of medication directly into the bone marrow.
commonly used in infants and toddlers who have poor accesst o their intravascular space? |
Intraosseous
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given into the peritoneal cavity,
used in dialysis patients? |
Intraperiotoneal
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given through the chest wall and directly into the pleural spce.
chemo pts use this method |
Intrapleural
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6 rights of medication administration?
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Medication
Dose Client Route Time Documentation |
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Nurse checks the medication lable 3 times, Name the steps?
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-before removing from shelf
-before opening package -before discarding package |
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Assessment before giving meds
Name the steps? |
1-review clients medical history
2-history of allergies 3-Medication data 4-diet history 5-clients ability to prepare doses and take medications correctly 6-assess physical or mental status 7-observe clients behavior for evidence of dependence or avoidance to meds 8-client knowledge to meds 9-determine need for intruction of meds |
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contraindications for giving oral medications via mouth is ?
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GI alterations
inability to swallow gastric suction |
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which medications cannot be crushed?
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buccal
sublingual enteric-coated sustained-released |
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how to administer crushed meds in Ng, GI tube?
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dissolve crushed tablets,gelatin capsules, powders in 15 to 30 ml of warm water.
give each meds seperately between 1 and 30 ml of water total amt of volume to the client 60 to 150 ml of water |
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administer nasal drops?
posterior pharynx? ethmoid or sphenoid sinus? frontal and maxillary sinus? |
posterior pharynx: tilt head backwards
ethmoid or sphenoid sinus: tilt head back over edge of bed or place small pillow under shoulder and tilt head back frontal and maxillary sinus: tilt head back over edge of bed or pillow with head turnes toward side to be treated. |