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73 Cards in this Set

  • Front
  • Back
What is an OINTMENT ?
An ointment is a greasy preparation which insoluble in water and does not absorb easily into the skin.(occlusive).
What is a CREAM ?
an emulsion of oil and water
absorbs well into skin
What is a PASTE ?
powder mixed in soft paraffin, liquid paraffin or non-greasy base.

a PASTE = POWDER + PARAFFIN
What is a SPRAY ?
A SPRAY is a dry powder in an aerosol can.
What is an ANTIMICROBIAL agent?
An antimicrobial agent is a compound that selectively destroys or inhibits the growth of micro-organisms. Also called "antiseptics" or "disinfectants".
An ANTIFUNGAL is....
An ANTIFUNGAL is a compound that selectively destroys or inhibits the growth of FUNGAL CELLS.
How do EMOLLIENTs work?
EMOLLIENTS help maintain the water content of the skin.
What do ASTRINGENTs do ?
Astringents contract living tissue and in some cases lessen secretions.
What are CAUSTICS ?
CAUSTICS are substances that are destructive to living tissue.
What is the action of a styptic?
stops bleeding
Name four mechanical methods of haemostasis used in podiatry
Methods of mechanical haemostasis:
1) tourniquets
2) direct digital pressure
3) elevating limb
4) sutures
Name some common chemical haemostats used in podiatry
Hydrogen Peroxide
Ferric Chloride (rarely used)
Silver Nitrate (rarely used)
Name a dressing that acts as a haemostat.
Calcium Alginate (brand name=KALTOSTAT) is a haemoststic dressing derived from seaweed.
How do haemostats work ?
1. mechanical action reduces blood flow to area enabling a clot to form
2. vasoconstricts small blood vessels by chemical means
3. physical plug caused by reaction between blood and dressing
State the function of antiseptics.
Antiseptics kill, inactivate or disable micro-organisms.
What is an antiseptic's mode of action?
a) bind to the Stratum Corneum
b) disrupts microbial cell wall
Name four factors that affect how well an antiseptic works
1. Duration of contact with micro-organism
2. Nature of infecting organism
3. Concentration of antiseptic
4. Temperature
What is a PROPHYLACTIC ?
A prophylactic is a PREVENTATIVE MEASURE. Derived from Greek meaning "an advance guard"
Properties of an IDEAL ANTISEPTIC ?
- rapid action
- broad spectrum
- not inhibited by organic matter
- remains on skin
- able to penetrate skin creases/crevices
- non-toxic
Disadvantages of ANTISEPTICS ?
- can reduce wound repair
- widespread use kills resident flora and allows transients to multiply
- cross-infection risk from open tubes of creams
Name three products that contain chlorhexidine, and the percentages in each.
Hydrex spray 0.5%
Bactigras gauze 0.5%
Hibiscrub wash 4%
What are the properties of chlorhexidine?
Broad spectrum antiseptic
Antifungal
Viricidal
What are the advantages of chlorhexidine as an antiseptic agent?
1) persistent effect for hours
2) low tissue toxicity
What are the properties of alcohol as a medicament?
Broad spectrum antiseptic
Astringent
Betadine spray contains what agent?
Povidone Iodine 2.5%
What characteristics does Povidone Iodine have that make it useful in podiatry?
1) iodine slow release renders it active for a long time
2) is active in presence of body fluids
What products contain iodine and in what concentrations?
Betadine spray 2.5%
Betadine scrub 7.5%
Betadine solution 10%
What clinical properties does iodine have?
Broad spectrum antiseptic
Kills spores
Kills viruses
What is the active ingredient in Anaflex cream?
polynoxylin 10%
What emollients contain Urea?
Calmurid 10%
Flexitol (varies)
Active agents in Calmurid?
Urea 10%
Lactic Acid 5%
What type of agent is Salicylic Acid?
Caustic-Keratolytic
Mode of action of Caustic-Keratolytics?
breaks down salt linkages in keratin molecule
allows water into the stratum corneum
What strength of Salicylic Acid is used in podiatric preparations?
60-75% w/w Salicylic Acid
Name some branded preparations containing Salicylic Acid.
Salactol
Bazuka
Podiatric uses of caustics-keratolytics?
Verucca Pedis
Heloma Durum
What would you advise your patient to do to neutralise Salicylic Acid dressings?
Soak foot in alkaline solution e.g. Sodium Bicarbonate
What type of agent is Silver Nitrate?
Caustic-protein precipitate
What is Silver Nitrate used for?
Verucca Pedis
Heloma Durum
Common preparation and strength of Silver Nitrate?
75% (but up to 95%)
What do silver nitrate sticks also contain?
Potassium Nitrate
What active ingredients does E45 contain?
Medical lanolin
White Soft Paraffin
What active ingredients does Aqueous Cream contain?
White Soft Paraffin
Liquid Paraffin
What is a styptic agent?
stops bloodflow
Name two styptic agents
Hydrogen Peroxide
Aluminium Sulphate
Name a haemostatic dressing - what is the active ingredient?
Kaltostat - seaweed alginate
Wat is the difference between an Ointment and a Cream?
Ointment - not absorbed by skin
Cream - absorbable emulsion
What are the two modes of action of emollients?
Address moisture loss from skin by either:
1) occluding (preventing water escaping)
2) providing water for absorption by skin
What is the action of an astringent?
contracts living tissue and
may lessen secretions
What does use of an antiseptic on the skin achieve?
it reduces total skin bacterial counts of both transient and resident flora
Antiseptic mode of action is dependent on what four factors?
1. Time in contact with micro-organism
2. Nature of infecting org
3. Concentration of the antiseptic
4. Temperature
What layer of the skin do antiseptics bind to?
the Stratum Corneum
State 4 properties of the ideal antiseptic
1) rapid action
2) no adverse effects
3) broad spectrum
4) active in presence of organic matter
5) penetrates crevices/cracks
Disadvantages of antiseptics?
Reduce Wound Repair
Habitual Use Disadvantages Resident Flora
What does alcohol do to the cell wall of bacteria?
denatures its protein
Name three classes of antifungal agents
Allylamines
Imidazoles
Polyenes
What kind of antifungal preparation is indicated for...plantar TPedis infection?
creams
What kind of antifungal preparation is indicated for nail infections?
Nail paints.
Name a proprietary nail paint, its active agent and the strength.
Loceryl (Amorolfine 5%)
Name three antifungal agents and their brand names.
Lamasil (Terbinafine)
Loceryl (Amorolfine)
Daktarin (Miconazole)
Canesten (Clotrimazole)
Standard supplementary advice to patients using topical antifungal agents?
treat shoes and socks as well as feet
beware reinfection from sharing (mats, towels)
State 4 reasons why a patient might need to use an emollient.
1) to prevent HK, lesions, fissures
2) systemic conditions can lead to dry skin
3) elderly skin holds less water
4) to compensate for constant handwashing
What kind of an agent is urea?
keratolytic
Name some emollients
Doublebass
Diprobase
Eucerin
Calmurid
E45
Name a podiatric use for an astringent.
Drying up interdigital maceration.
What kind of agent would you use if a patient was hyperhydrotic?
Astringent, such as potassium permanganate
What medicament causes a black eschar, and what kind of agent is it?
Silver Nitrate
Its a caustic-protein precipitant

or

Pyrogallic Acid 40%
a Caustic-Reducing agent
How can silver nitrate be neutralised?
Hypertonic saline solution
Name two important contraindications to caustic therapy
1) impaired tissue viability
2) around bony prominences, or in absence of fatty padding
What kind of agent is Monchloracetic Acid?
a Hydrolysing agent
How do hydrolysing agents work?
by hydrolysing proteins in keratin, converting them into soluble proteins
What to remember when using hydrolysing agents?
Mask the area
If problems, soak in bicarbonate of soda solution
What is Opsite?
A polyurethane dressing spray